Announcements Trials
Browse Landscape

Phase

Phase 2 149Phase 1 112Phase 3 84Phase 1/2 37Phase NA 7Phase 2/3 7Phase EARLY_PHASE1 6Phase 4 2

Status

Terminated 2Withdrawn 1Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 5Other solid neoplasm 1Lymphoid 1

Conditions

Glioma 4Neoplasms 2Brain Neoplasms 2Retinoblastoma 1Recurrence 1Neuroblastoma 1Lymphoma, Follicular 1

Interventions

Magnetic Resonance Spectroscopy 61Cyclophosphamide 57pembrolizumab 39fludarabine 38Radiotherapy 30Nivolumab 30Biopsy 27Metformin 23Fluorodeoxyglucose F18 22Bevacizumab 22Specimen Handling 21Temozolomide 18Cisplatin 18Radiosurgery 17Carboplatin 16Fluorouracil 15Paclitaxel 14Dexamethasone 14Radiation 13Gemcitabine 13Etoposide 13Rituximab 12Positron Emission Tomography Computed Tomography 12Letrozole 12Irinotecan 12gallium 68 PSMA-11 11durvalumab 11atezolizumab 11X-Rays 11Surgical Procedures, Operative 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Topotecan × Clear all
NCT04947501 2025-08-05

A Study of N9 Chemotherapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

Phase EARLY_PHASE1 Active not recruiting
26 enrolled
CNS

Neoplasms, Neuroblastoma

NCT06972602 2025-05-15

High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed

Eye & ENT Hospital of Fudan University

Phase EARLY_PHASE1 Recruiting
10 enrolled
Other solid neoplasm

Recurrence, Retinoblastoma

NCT03927274 2023-05-25

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

H. Lee Moffitt Cancer Center and Research Institute

Phase EARLY_PHASE1 Terminated
3 enrolled
CNS

Brain Neoplasms, Glioma

NCT02500459 2019-03-01

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Terminated
9 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms

NCT03193463 2019-03-01

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Withdrawn
CNS

Glioma

NCT02278510 2017-03-31

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Completed
3 enrolled
CNSLymphoid

Glioma, Lymphoma, Follicular

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