Announcements Trials
Browse Landscape

Phase

Phase 2 88Phase 1 64Phase 1/2 19Phase 3 14Phase EARLY_PHASE1 6Phase NA 5Phase 2/3 2Phase 4 1

Status

Terminated 2Withdrawn 1Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 5Other solid neoplasm 1Lymphoid 1

Conditions

Glioma 4Neoplasms 2Brain Neoplasms 2Retinoblastoma 1Recurrence 1Neuroblastoma 1Lymphoma, Follicular 1

Interventions

Magnetic Resonance Spectroscopy 59Cyclophosphamide 44pembrolizumab 34Radiotherapy 30fludarabine 27Nivolumab 26Biopsy 26Metformin 22Fluorodeoxyglucose F18 22Specimen Handling 20Bevacizumab 20Temozolomide 17Radiosurgery 17Cisplatin 16Carboplatin 14Fluorouracil 13Dexamethasone 13Paclitaxel 12Gemcitabine 12Etoposide 12gallium 68 PSMA-11 11durvalumab 11X-Rays 11Surgical Procedures, Operative 11Radiation 11Positron Emission Tomography Computed Tomography 11Letrozole 11Irinotecan 11Ipilimumab 11Surveys and Questionnaires 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × OTHER × Topotecan × Clear all
NCT04947501 2025-08-05

A Study of N9 Chemotherapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

Phase EARLY_PHASE1 Active not recruiting
26 enrolled
CNS

Neoplasms, Neuroblastoma

NCT06972602 2025-05-15

High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed

Eye & ENT Hospital of Fudan University

Phase EARLY_PHASE1 Recruiting
10 enrolled
Other solid neoplasm

Recurrence, Retinoblastoma

NCT03927274 2023-05-25

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

H. Lee Moffitt Cancer Center and Research Institute

Phase EARLY_PHASE1 Terminated
3 enrolled
CNS

Brain Neoplasms, Glioma

NCT02500459 2019-03-01

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Terminated
9 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms

NCT03193463 2019-03-01

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Withdrawn
CNS

Glioma

NCT02278510 2017-03-31

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Completed
3 enrolled
CNSLymphoid

Glioma, Lymphoma, Follicular

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