Clinical Trials

Liposarcoma, Sarcoma

NCT02367924 2023-06-22

YonSar

Completed

130 enrolled

NCT03690739 2022-02-24

Evaluation of Symptom Benefit Rate of Trabectedin/PLD in Patients With Recurrent Ovarian Cancer

Phase 3 Terminated

9 enrolled

Ovarian Neoplasms

NCT02825420 2021-10-29

NIMES-ROC

Completed

220 enrolled 27 charts

Ovarian Neoplasms

NCT03056599 2021-09-24

Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma

Phase 1 Completed

23 enrolled

NCT01846611 2019-04-01

A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

581 enrolled 14 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms

NCT01692678 2018-07-11

A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma

16 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT00210665 2017-10-10

A Study to Provide Access to Trabectedin in Participants With Locally Advanced or Metastatic Soft Tissue Sarcoma Who Have Persistent or Recurrent Disease and Who Are Not Expected to Benefit From Currently Available Standard of Care Treatment

No longer available

NCT01343277 2016-08-26

A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma

579 enrolled 13 charts

Leiomyosarcoma

NCT01273493 2016-02-15

A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction

Phase 1 Completed

15 enrolled

Liver Diseases, Neoplasm Metastasis, Hepatic Insufficiency

NCT00796120 2015-12-10

An Efficacy and Safety Study of Trabectedin Versus Doxorubicin-Based Chemotherapy in Participants With Translocation-Related Sarcomas (TRS)

121 enrolled 10 charts

Other solid neoplasmThoracic

NCT01267084 2015-10-14

A Study to Assess the Potential Effects of Ketoconazole on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies

Phase 1/2 Completed

12 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT00027508 2015-02-24

Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma

Phase 2 Terminated

Mesothelioma, Malignant

NCT00060944 2014-09-08

A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer

271 enrolled 13 charts

Leiomyosarcoma, Liposarcoma, Neoplasm Metastasis, Neoplasms

NCT00113607 2014-06-27

An Efficacy and Safety Study for Yondelis (Trabectedin) in Patients With Advanced Relapsed Ovarian Cancer

672 enrolled 14 charts

Ovarian Neoplasms

NCT00579501 2014-05-07

Safety and Efficacy Study of Trabectedin for the Treatment of Localized Myxoid / Round Cell Liposarcoma

29 enrolled 7 charts

Liposarcoma, Liposarcoma, Myxoid

NCT00786838 2014-04-11

A Study to Assess the Potential Effects of a Single-Dose Administration of Trabectedin on the QT Intervals of the Electrocardiogram

76 enrolled 17 charts

BreastGynecologicSarcoma

Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Sarcoma

NCT00072670 2014-04-08

A Phase 2 Study of Trabectedin (Yondelis) in Adult Male Participants With Advanced Prostate Cancer

59 enrolled

Genitourinary

Prostatic Neoplasms

NCT00580112 2014-02-25

An Efficacy Study of Trabectedin in the Treatment of Participants With Specific Subtypes of Metastatic Breast Cancer

127 enrolled

Breast

Breast Neoplasms

NCT00050414 2013-01-10

A Study of Trabectedin in Patients With Advanced Ovarian Cancer

147 enrolled

Adnexal Diseases, Endocrine Gland Neoplasms, Genital Diseases, Female, Neoplasms, Neoplasms by Site, Ovarian Diseases, Ovarian Neoplasms

NCT00102609 2013-01-10

A Safety Study Utilizing Yondelis and Doxorubicin in Patients With a Type of Cancer Called Soft Tissue Sarcoma

Phase 1 Completed

41 enrolled

Neoplasms, Neoplasms by Histologic Type, Sarcoma, Neoplasms, Connective and Soft Tissue

NCT00050440 2013-01-08

Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma

50 enrolled

Carcinoma, Neoplasms, Uterine Neoplasms, Endometrial Neoplasms

NCT00050427 2011-04-28

A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer