Clinical Trials

Liposarcoma, Sarcoma

NCT03690739 2022-02-24

Evaluation of Symptom Benefit Rate of Trabectedin/PLD in Patients With Recurrent Ovarian Cancer

Phase 3 Terminated

9 enrolled

Ovarian Neoplasms

NCT03056599 2021-09-24

Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma

Phase 1 Completed

23 enrolled

NCT01846611 2019-04-01

A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

581 enrolled 14 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms

NCT01692678 2018-07-11

A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma

16 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT01343277 2016-08-26

A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma

579 enrolled 13 charts

Leiomyosarcoma

NCT01273493 2016-02-15

A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction

Phase 1 Completed

15 enrolled

Liver Diseases, Neoplasm Metastasis, Hepatic Insufficiency

NCT00796120 2015-12-10

An Efficacy and Safety Study of Trabectedin Versus Doxorubicin-Based Chemotherapy in Participants With Translocation-Related Sarcomas (TRS)

121 enrolled 10 charts

Other solid neoplasmThoracic

NCT01267084 2015-10-14

A Study to Assess the Potential Effects of Ketoconazole on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies

Phase 1/2 Completed

12 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT00027508 2015-02-24

Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma

Phase 2 Terminated

Mesothelioma, Malignant

NCT00060944 2014-09-08

A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer

271 enrolled 13 charts

Leiomyosarcoma, Liposarcoma, Neoplasm Metastasis, Neoplasms

NCT00113607 2014-06-27

An Efficacy and Safety Study for Yondelis (Trabectedin) in Patients With Advanced Relapsed Ovarian Cancer

672 enrolled 14 charts

Ovarian Neoplasms

NCT00579501 2014-05-07

Safety and Efficacy Study of Trabectedin for the Treatment of Localized Myxoid / Round Cell Liposarcoma

29 enrolled 7 charts

Liposarcoma, Liposarcoma, Myxoid

NCT00786838 2014-04-11

A Study to Assess the Potential Effects of a Single-Dose Administration of Trabectedin on the QT Intervals of the Electrocardiogram

76 enrolled 17 charts

BreastGynecologicSarcoma

Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Sarcoma

NCT00072670 2014-04-08

A Phase 2 Study of Trabectedin (Yondelis) in Adult Male Participants With Advanced Prostate Cancer

59 enrolled

Genitourinary

Prostatic Neoplasms

NCT00580112 2014-02-25

An Efficacy Study of Trabectedin in the Treatment of Participants With Specific Subtypes of Metastatic Breast Cancer

127 enrolled

Breast

Breast Neoplasms

NCT00050414 2013-01-10

A Study of Trabectedin in Patients With Advanced Ovarian Cancer

147 enrolled

Adnexal Diseases, Endocrine Gland Neoplasms, Genital Diseases, Female, Neoplasms, Neoplasms by Site, Ovarian Diseases, Ovarian Neoplasms

NCT00102609 2013-01-10

A Safety Study Utilizing Yondelis and Doxorubicin in Patients With a Type of Cancer Called Soft Tissue Sarcoma

Phase 1 Completed

41 enrolled

Neoplasms, Neoplasms by Histologic Type, Sarcoma, Neoplasms, Connective and Soft Tissue

NCT00050440 2013-01-08

Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma

50 enrolled

Carcinoma, Neoplasms, Uterine Neoplasms, Endometrial Neoplasms

NCT00050427 2011-04-28

A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer