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NCT00844064 2019-02-15

Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2

Phase 1 Completed

DermatologicGastrointestinal

Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT00761280 2014-11-14

SAPPHIRE

Phase 3 Terminated

27 enrolled 28 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00431561 2013-12-03

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Camurati-Engelmann Syndrome, Glioblastoma, Neoplasms