Clinical Trials

39 enrolled

GastrointestinalLymphoid

Cancer That is Associated With a Chronic Viral Infection

NCT01817751 2024-07-17

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

47 enrolled 13 charts

CNS

Brain Neoplasms, Glioblastoma, Glioma, Neurologic Manifestations

NCT02624128 2023-11-13

V-CHANCE

39 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT04310176 2023-11-13

REVOLUTION

200 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

38 enrolled 53 charts

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT02124174 2021-04-26

Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS

Classical hematologyMyeloidOther hematologic neoplasm

50 enrolled

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01900730 2020-02-25

Study of Valproic Acid (VPA) vs Placebo to Shorten Time of Indwelling Pleural Catheter

3 enrolled 6 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT00414310 2019-05-21

Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)

153 enrolled 8 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00670046 2018-09-28

Valproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate Cancer

15 enrolled 11 charts

Genitourinary

Prostatic Neoplasms

NCT00867672 2016-08-31

DECIDER

Other hematologic neoplasm

204 enrolled

Leukemia, Myeloid, Acute

NCT01695122 2016-02-23

Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

14 enrolled

Head & Neck

Head and Neck Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00634205 2015-02-12

Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma

Other solid neoplasmThoracic

45 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT00759824 2015-02-12

A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and Etoposide

64 enrolled

Thoracic

Small Cell Lung Carcinoma

NCT00525135 2015-02-03

Valproic Acid (Depakote ER) in Patients With Advanced Thyroid Cancer

5 enrolled 2 charts

Head & Neck

Head and Neck Neoplasms

NCT00382590 2012-08-07

Azacytidine With Valproic Acid Versus Ara-C in Acute Myeloid Leukemia (AML)/ Myelodysplastic Syndrome (MDS) Patients

11 enrolled 6 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00326170 2012-06-15

Phase II 5-Azacytidine Plus VPA Plus ATRA

34 enrolled 5 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01011998 2011-09-27

A Study of Imatinib and Valproic Acid in Patients With Chronic Myelogenous Leukemia (CML)

Phase 2 Withdrawn

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00524667 2011-07-20

HDAC Inhibitor Valproic Acid as an Effective Therapy for Chronic Lymphocytic Leukemia

LymphoidOther hematologic neoplasm

6 enrolled

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01333631 2011-04-12

Valproic Acid With Chemoradiotherapy for Pancreatic Cancer