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Phase

Phase 1 5Phase EARLY_PHASE1 1Phase 3 1Phase 1/2 1

Status

Completed 24Terminated 8Withdrawn 5Unknown 2Suspended 1Active not recruiting 1

Sponsor Class

OTHER 3INDUSTRY 2

Study Type

Interventional 5

Sponsor

Cancer Type

Dermatologic 4Tumor-Agnostic 1CNS 1

Conditions

Melanoma 4Neoplasms 2Brain Neoplasms 1

Interventions

Cyclophosphamide 35Cisplatin 24fludarabine 23Radiotherapy 23Paclitaxel 21Carboplatin 20pembrolizumab 18Nivolumab 18Magnetic Resonance Spectroscopy 18Specimen Handling 17fludarabine phosphate 15Gemcitabine 15Biopsy 15Cytarabine 14Radiation 11Filgrastim 11Doxorubicin 11Docetaxel 11Dexamethasone 11Radiosurgery 10Granulocyte Colony-Stimulating Factor 10Etoposide 10Melphalan 9Ipilimumab 9venetoclax 8Rituximab 8Calcium Dobesilate 8trametinib 7ibrutinib 7durvalumab 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Withdrawn × Vemurafenib × Clear all
NCT02145910 2025-05-02

Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases

Thomas Jefferson University

Phase 1 Withdrawn
CNSDermatologic

Brain Neoplasms, Melanoma

NCT02068079 2019-01-30

A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic Melanoma

Duke University

Phase 1 Withdrawn
Dermatologic

Melanoma

NCT01843738 2017-05-24

Radiation Use During Vemurafenib Treatment

University of Utah

Phase 1 Withdrawn
Dermatologic

Melanoma

NCT01765556 2016-11-02

A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma

Hoffmann-La Roche

Phase 1 Withdrawn
Dermatologic

Melanoma, Neoplasms

NCT01974258 2016-11-02

Safety, Tolerability, and Pharmacokinetics of Onartuzumab Combined With Vemurafenib and/or Cobimetinib in Cancer Patients

Hoffmann-La Roche

Phase 1 Withdrawn
Tumor-Agnostic

Neoplasms

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