Clinical Trials

Burkitt Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse

NCT02316340 2024-01-05

Vorinostat Plus Hydroxychloroquine Versus Regorafenib in Colorectal Cancer

42 enrolled 8 charts

Gastrointestinal

Colorectal Neoplasms

NCT04190056 2023-08-31

Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer

1 enrolled 4 charts

Anatomic Stage IV Breast Cancer AJCC v8

NCT02035137 2022-06-08

N2011-01

114 enrolled 13 charts

CNS

Neuroblastoma

NCT01617226 2021-05-05

RAvVA

260 enrolled

Leukemia, Myeloid, Acute

NCT03509207 2020-08-04

Vorinostat (SAHA) in Uterine Sarcoma

3 enrolled 6 charts

GynecologicSarcoma

Leiomyosarcoma, Endometrial Stromal Tumors

NCT02395627 2020-07-07

Reversing Therapy Resistance With Epigenetic-Immune Modification

38 enrolled 18 charts

Breast Neoplasms

NCT00992446 2020-03-18

Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

27 enrolled 13 charts

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT00948064 2020-02-24

Vorinostat in Combination With Azacitidine in Patients With Newly-Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

MyeloidOther hematologic neoplasm

110 enrolled 9 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00798720 2019-12-13

Vorinostat and Bortezomib as Third-line Treatment in Advanced Non-small Cell Lung Cancer

18 enrolled 16 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00958074 2018-10-18

Vorinostat in Patients With Primary Cutaneous T-Cell Lymphoma

11 enrolled 11 charts

DermatologicLymphoid

Lymphoma, T-Cell, Cutaneous

NCT00918489 2018-10-17

SAHA-I

40 enrolled

Sarcoma

Neoplasm Metastasis, Sarcoma

NCT01790568 2018-08-13

Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant

26 enrolled 9 charts

Graft vs Host Disease, Hematologic Neoplasms

NCT00720876 2018-08-07

Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin Lymphoma

30 enrolled 8 charts

Lymphoma, Lymphoma, Follicular, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT02419755 2018-03-07

Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies

12 enrolled 10 charts

Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00818649 2017-12-28

Bortezomib and Vorinostat in Treating Patients With High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Classical hematologyMyeloidOther hematologic neoplasm

16 enrolled 7 charts

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00882206 2017-12-28

Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia

15 enrolled 8 charts

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01312818 2017-12-28

Bortezomib, Vorinostat and Dexamethasone for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)

2 enrolled 6 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00764517 2017-12-11

Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma

57 enrolled 14 charts

Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT00837174 2017-09-19

COMBOSTAT

Burkitt Lymphoma, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Peripheral, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00673153 2017-06-01

Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

31 enrolled 11 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT01738646 2017-03-06

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

48 enrolled 10 charts

CNS

Brain Neoplasms, Glioblastoma, Glioma

NCT01501370 2016-05-10

ZLd_Ld

Plasma cell

Multiple Myeloma, Neoplasms, Plasma Cell

NCT01578343 2016-04-15

ZOLINZA

20 enrolled

Recurrence, Lymphoma, Mantle-Cell

NCT01500538 2016-02-15

VEIL

Classical hematologyLymphoid

1 enrolled

Lymphoma, Lymphoma, Follicular, Thrombocytopenia, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT00656617 2015-03-09

Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

MyeloidOther hematologic neoplasm

106 enrolled 6 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00365599 2014-11-21

Phase II Trial of SAHA & Tamoxifen for Patients With Breast Cancer

43 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis, Bulbo-Spinal Atrophy, X-Linked

NCT02114502 2014-07-11

Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma

Plasma cell

Multiple Myeloma, Recurrence, Neoplasms, Plasma Cell

NCT00942266 2014-06-23

Vorinostat, Fluorouracil, and Leucovorin Calcium in Treating Patients With Metastatic Colorectal Cancer That Has Not Responded to Previous Treatment

58 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT01600742 2014-01-09

Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis

4 enrolled

CNS

Brain Neoplasms

NCT01194427 2013-05-17

A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast Cancer

2 enrolled 3 charts

Breast Neoplasms

NCT00810576 2012-08-07

Combination of Vorinostat and Bortezomib in Relapsed or Refractory T-Cell Non-Hodgkin's Lymphoma

1 enrolled 3 charts

DermatologicLymphoid

Subcutaneous panniculitis-like T-cell lymphoma, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Enteropathy-Associated T-Cell Lymphoma

NCT01492881 2012-05-11

Study of Vorinostat With Doxil and Bortezomib for Patients With Relapsed/Refractory Multiple Myeloma

Plasma cell

Multiple Myeloma

NCT00866762 2011-12-12

A Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia

Phase 2 Unknown

60 enrolled

Myeloid

Hematologic Diseases, Polycythemia, Polycythemia Vera, Thrombocythemia, Essential

NCT01039363 2009-12-25

Vorinostat Combined With Gemtuzumab Ozogamicin, Idarubicin and Cytarabine in Acute Myeloid Leukemia

Phase 2 Unknown

27 enrolled