Clinical Trials Browser

OTHER × Interventional × Zoledronic Acid × Clear all

NCT07043608 2026-05-01

ZAMBONI

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT03295981 2026-04-22

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

Phase 3 Recruiting

Giant Cell Tumor of Bone

NCT06374459 2026-04-20

Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

Phase 1/2 Recruiting

Breast Neoplasms

NCT04549207 2026-04-07

Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer

Phase 4 Active not recruiting

Breast Neoplasms

NCT06625190 2026-03-11

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Phase 1/2 Recruiting

Chordoma, Myoepithelioma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT03664687 2026-02-09

REaCT-ZOL

Phase 4 Completed

Breast Neoplasms

NCT05400603 2025-12-26

Aflac-NBL-2002

Phase 1 Recruiting

Neuroblastoma, Osteosarcoma

NCT06759064 2025-11-19

IPIZA

Phase 1/2 Recruiting

Gastrointestinal

Adenocarcinoma, Ascites, Stomach Neoplasms

NCT03173976 2025-11-06

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

Phase 1 Active not recruiting

Chondrosarcoma

NCT02508038 2025-10-16

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

Phase 1 Recruiting

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Leukemia, Myeloid, Acute, Neuroectodermal Tumors, Primitive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05080790 2025-08-17

DiTuSarc

Phase 2 Completed

Leiomyosarcoma

NCT06876636 2025-07-29

Zoledronic Acid Combined With EC-T for Triple-Negative Breast Cancer

Phase NA Active not recruiting

Breast Cancer Metastatic

NCT06513624 2025-07-25

ETC-159-02

Phase 1 Recruiting

With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer

NCT00470223 2025-06-08

OS2006

Phase 3 Active not recruiting

Sarcoma, Osteosarcoma

NCT02517918 2025-06-08

METZOLIMOS

Phase 1 Completed

23 enrolled 15 charts

Osteosarcoma

NCT03073785 2025-05-25

Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer

Phase 2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT03336983 2024-08-01

BonEnza

Phase 2 Completed

Prostatic Neoplasms

NCT00733538 2024-04-12

IFM-01-04

Phase 4 Completed

Multiple Myeloma

NCT00525759 2023-11-24

ANZAC

Phase 2 Completed

Breast Neoplasms

NCT03358017 2023-10-19

YAPPETIZER

Phase 2 Completed

Triple Negative Breast Neoplasms

NCT05866172 2023-05-19

HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

Phase 3 Unknown

Gastrointestinal

Carcinoma, Hepatocellular

NCT00885326 2023-04-10

N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma

Phase 1 Completed

Neuroblastoma

NCT00412022 2023-03-24

HOBOE

Phase 3 Unknown

Breast Neoplasms

NCT02286830 2023-02-17

Magnolia

Phase 4 Completed

Multiple Myeloma, Osteolysis, Osteonecrosis

NCT00458796 2022-05-27

Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

Phase NA Terminated

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Pain, Breast Neoplasms, Male

NCT00566618 2022-02-25

Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis

Phase 1/2 Completed

31 enrolled 8 charts

Breast Neoplasms

NCT05164952 2021-12-21

Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole

Phase 3 Unknown

Breast Neoplasms

NCT03408652 2021-10-22

MOSCAR

Phase 3 Terminated

Carcinoma, Renal Cell

NCT01623908 2021-06-22

BLAZE

Phase NA Terminated

Bone Diseases, Metabolic, Breast Neoplasms

NCT00058188 2020-12-08

Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation

Phase 3 Terminated

Osteoporosis, Prostatic Neoplasms

NCT02721433 2020-12-02

REaCT-BTA

Phase 4 Completed

BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms

NCT00079001 2020-05-12

Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

Phase 3 Completed

645 enrolled 13 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT00295867 2020-05-12

Zoledronate in Treating Bone Marrow Micrometastases in Women With Stage I, Stage II, or Stage III Breast Cancer

Phase 2 Completed

45 enrolled 9 charts

Breast Neoplasms

NCT01409811 2020-05-08

Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid

Phase NA Terminated

9 enrolled 3 charts

Breast Neoplasms, Carcinoma, Ductal, Breast

NCT01087008 2020-04-06

AZABACHE

Phase 4 Completed

Multiple Myeloma

NCT00226954 2020-03-18

Zoledronic Acid With Intermittent Hormonal Therapy in Patients With Prostate Cancer

Phase 2 Terminated

Urologic Neoplasms

NCT00213980 2019-11-27

Bone Mineral Density Effects of Zoledronate in Postmenopausal Women With Breast Cancer

Phase 2 Completed

68 enrolled 11 charts

Breast Neoplasms

NCT00582556 2019-11-26

Zometa on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Ablation Therapy

Phase 2 Completed

44 enrolled 8 charts

Prostatic Neoplasms

NCT00582790 2019-11-25

Study of IL2 in Combination With Zoledronic Acid in Patients With Kidney Cancer

Phase 2 Terminated

12 enrolled 8 charts

Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasm Metastasis

NCT01772719 2019-11-18

Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid

Phase NA Terminated

7 enrolled 4 charts

Multiple Myeloma

NCT00987636 2019-10-22

EWING2008

Phase 3 Completed

Neoplasm Metastasis, Sarcoma, Ewing

NCT00436917 2019-09-11

Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

Phase NA Completed

60 enrolled 23 charts

Breast Neoplasms, Osteoporosis

NCT01367288 2019-05-28

NEOZOL

Phase 2 Completed

Breast Neoplasms, Neovascularization, Pathologic

NCT03932071 2019-05-06

Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma

Phase 4 Unknown

Lung Metastases

NCT00130494 2019-04-16

Zoledronic Acid Administration to Metastatic Breast Cancer Patients With Non-symptomatic Bone Lesions

Phase 3 Terminated

Breast Neoplasms, Neoplasm Metastasis

NCT01205646 2019-04-12

PET Scanning to Evaluate Zoledronate Efficacy in Metastatic Prostate Cancer

Phase NA Completed

11 enrolled 7 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT02480634 2019-01-16

Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer

Phase 4 Unknown

Carcinoma, Non-Small-Cell Lung

NCT00869206 2018-11-07

Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

Phase 3 Completed

1,822 enrolled 19 charts

BreastGenitourinaryPlasma cell

Breast Neoplasms, Multiple Myeloma, Pain, Prostatic Neoplasms

NCT02347163 2018-11-06

Pre-operative Zoledronate in Triple Negative Breast Cancer

Phase 2 Terminated

Breast Neoplasms

NCT01194440 2018-09-12

Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms

Phase 2 Completed

63 enrolled 7 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating