Clinical Trials Browser

Phase 1 × Completed × abemaciclib × Clear all

Breast Neoplasms, Neoplasm Metastasis, Recurrence

NCT05999968 2026-03-05

Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment

Phase 1 Completed

10 enrolled

Genitourinary

Prostatic Neoplasms

NCT04481113 2026-01-29

Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer

Phase 1 Completed

8 enrolled

Breast

Unilateral Breast Neoplasms

NCT04627064 2025-07-25

ABEMA Alone or in COMBO With MK-6482

Phase 1 Completed

11 enrolled 9 charts

Genitourinary

Carcinoma, Renal Cell

NCT03099174 2025-06-24

This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer

Phase 1 Completed

133 enrolled 26 charts

Breast

Breast Neoplasms, Neoplasms

NCT05759949 2025-05-16

First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors

Phase 1 Completed

41 enrolled

Breast

Breast Neoplasms

NCT02791334 2024-09-27

PACT

Phase 1 Completed

164 enrolled

BreastDermatologicGastrointestinal

Breast Neoplasms, Melanoma, Pancreatic Neoplasms

NCT01394016 2024-09-19

A Phase 1 Study of LY2835219 In Participants With Advanced Cancer

Phase 1 Completed

225 enrolled 31 charts

Advanced Cancer

NCT02644460 2023-10-26

AflacST1501

Phase 1 Completed

53 enrolled

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT04514159 2023-02-01

A Study of ZN-c5 and Abemaciclib in Participants With Breast Cancer

Phase 1 Completed

14 enrolled

Breast

Breast Neoplasms

NCT02857270 2022-11-22

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

Phase 1 Completed

210 enrolled

DermatologicGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Colorectal Neoplasms

NCT02688088 2022-10-18

A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body

Phase 1 Completed

48 enrolled 30 charts

Tumor-Agnostic

Neoplasm Metastasis

NCT01655225 2022-04-08

A Study of LY3023414 in Participants With Advanced Cancer

Phase 1 Completed

156 enrolled

BreastLymphoidOther solid neoplasmThoracic

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Lymphoma, Non-Hodgkin, Mesothelioma, Neoplasm Metastasis

NCT04071262 2021-09-21

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer

Phase 1 Completed

6 enrolled

Advanced Cancer

NCT02919696 2020-09-25

A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers

Phase 1 Completed

26 enrolled 16 charts

Tumor-Agnostic

Neoplasm Metastasis

NCT02079636 2020-09-11

A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC)

Phase 1 Completed

142 enrolled 36 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02014129 2020-08-24

A Study of LY2835219 in Japanese Participants With Advanced Cancer

Phase 1 Completed

12 enrolled 11 charts

Lymphoid

Lymphoma, Neoplasm Metastasis

NCT02411591 2020-07-09

A Study of Necitumumab and Abemaciclib in Participants With Non-Small Cell Lung Cancer (NSCLC)

Phase 1 Completed

66 enrolled 20 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT02745769 2019-03-05

A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents

Phase 1 Completed

23 enrolled

GastrointestinalLymphoid

Colorectal Neoplasms, Lymphoma, Mantle-Cell

NCT02117648 2019-01-07

A Study of LY2835219 in Participants With Cancer

Phase 1 Completed

26 enrolled 11 charts

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

Clinical Trials

ONO-4578-06:Phase I Study of ONO-4578 and Letrozole Plus CDK4 /6 Inhibitors in Breast Cancer

Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment

Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer

ABEMA Alone or in COMBO With MK-6482

This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer

First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors

PACT

A Phase 1 Study of LY2835219 In Participants With Advanced Cancer

AflacST1501

A Study of ZN-c5 and Abemaciclib in Participants With Breast Cancer

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body

A Study of LY3023414 in Participants With Advanced Cancer

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer

A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers

A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC)

A Study of LY2835219 in Japanese Participants With Advanced Cancer

A Study of Necitumumab and Abemaciclib in Participants With Non-Small Cell Lung Cancer (NSCLC)

A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents

A Study of LY2835219 in Participants With Cancer