Clinical Trials Browser

Phase 2 × Completed × abemaciclib × Clear all

NCT04010357 2026-05-12

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

Phase 2 Completed

Small Cell Lung Carcinoma

NCT03643510 2026-03-16

Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer

Phase 2 Completed

Adenocarcinoma of Endometrium

NCT04603183 2025-12-12

ABIGAIL

Phase 2 Completed

Breast Cancer Metastatic

NCT04352777 2025-07-20

Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

Phase 2 Completed

Breast Neoplasms

NCT04552769 2025-06-05

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Phase 2 Completed

9 enrolled 10 charts

EndocrineHead & Neck

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT04432454 2025-02-13

ELAINEII

Phase 2 Completed

Breast Neoplasms

NCT02675231 2024-11-26

monarcHER

Phase 2 Completed

237 enrolled 25 charts

Hormone Receptor Positive Breast Cancer

NCT04408924 2024-06-25

CYCLONE 1

Phase 2 Completed

44 enrolled 21 charts

Metastatic Castration-Resistant Prostate Cancer

NCT03703466 2024-04-02

A Study of Abemaciclib (LY2835219) With and Without Food in Participants With Metastatic Breast Cancer

Phase 2 Completed

72 enrolled 19 charts

Breast Neoplasms

NCT03339843 2024-03-15

MiMe-A

Phase 2 Completed

GastrointestinalGenitourinaryGynecologic

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Neoplasms, Urologic Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT01739309 2023-09-21

Study of LY2835219 for Mantle Cell Lymphoma

Phase 2 Completed

28 enrolled 20 charts

Lymphoma, Non-Hodgkin, Lymphoma, Mantle-Cell

NCT03356223 2023-02-23

ABORL

Phase 2 Completed

Head and Neck Neoplasms, Neoplasm Metastasis

NCT03292250 2022-03-29

Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02450539 2021-08-13

A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer

Phase 2 Completed

159 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT02308020 2020-12-19

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain

Phase 2 Completed

162 enrolled 25 charts

BreastCNSDermatologicThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT02441946 2020-06-17

neoMONARCH

Phase 2 Completed

224 enrolled 20 charts

Breast Neoplasms

NCT02102490 2020-01-21

MONARCH 1

Phase 2 Completed

132 enrolled 17 charts

Breast Neoplasms

NCT02981342 2019-11-20

A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma

Phase 2 Completed

106 enrolled 24 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02831530 2018-03-29

ABC-POP

Phase 2 Completed

Breast Neoplasms