NCT02586857 2026-03-25A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)Acerta Pharma BVPhase 1/2 Active not recruiting24 enrolled 10 charts
NCT02029443 2026-02-06ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic LeukemiaAcerta Pharma BVPhase 1/2 Active not recruiting306 enrolled 26 charts
NCT03932331 2026-01-29Study of Acalabrutinib in Chinese Adult Subjects With Relapsed or Refractory Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia or Other B-cell MalignanciesAstraZenecaPhase 1/2 Active not recruiting105 enrolled 34 charts
NCT02328014 2025-12-09Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell MalignanciesAcerta Pharma BVPhase 1/2 Completed40 enrolled 12 charts
NCT02180711 2025-10-15Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin LymphomaAcerta Pharma BVPhase 1/2 Active not recruiting113 enrolled 19 charts
NCT03492125 2025-04-10A Study Of The Selective PKC-β Inhibitor MS- 553MingSight Pharmaceuticals, IncPhase 1/2 Terminated60 enrolled 20 charts
NCT04630756 2025-04-09AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood CancerAstraZenecaPhase 1/2 Completed40 enrolled 31 charts
NCT04502394 2022-08-04Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLLKartos Therapeutics, Inc.Phase 1/2 Unknown84 enrolled
NCT03205046 2021-01-06A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell MalignanciesAcerta Pharma BVPhase 1/2 Terminated25 enrolled 11 charts