Announcements Trials
Browse Landscape

Phase

Phase 1 4Phase 2 2Phase 1/2 1

Status

Completed 10Terminated 7Active not recruiting 2

Sponsor Class

INDUSTRY 7NIH 3OTHER 2

Study Type

Interventional 7

Sponsor

Cancer Type

Other solid neoplasm 3Thoracic 2Head & Neck 1Gynecologic 1Gastrointestinal 1

Conditions

Advanced Solid Tumours 2Uterine Cervical Neoplasms 1Stomach Neoplasms 1Previously Treated Non Small Cell Lung Cancer 1Lung Neoplasms 1Head and Neck Neoplasms 1Esophageal Neoplasms 1Advanced Solid Tumors 1

Interventions

pembrolizumab 184Carboplatin 130Paclitaxel 123Gemcitabine 122Docetaxel 96Cyclophosphamide 89Nivolumab 88Cisplatin 87Rituximab 71Dexamethasone 68Pemetrexed 64Bevacizumab 64Capecitabine 60atezolizumab 54fludarabine 49Azacitidine 49Fluorouracil 48130-nm albumin-bound paclitaxel 43venetoclax 41Trastuzumab 41Irinotecan 41Cetuximab 40Leucovorin 36Ipilimumab 36Erlotinib Hydrochloride 34Fulvestrant 32Cytarabine 32avelumab 31Oxaliplatin 31Albumin-Bound Paclitaxel 31

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Terminated × INDUSTRY × adavosertib × Clear all
NCT01047007 2023-09-21

A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005

Merck Sharp & Dohme LLC

Phase 1 Terminated
11 enrolled 10 charts
GastrointestinalHead & Neck

Esophageal Neoplasms, Head and Neck Neoplasms, Stomach Neoplasms

NCT01076400 2023-09-18

MK-1775-008

Merck Sharp & Dohme LLC

Phase 1/2 Terminated
7 enrolled 6 charts
Gynecologic

Uterine Cervical Neoplasms

NCT04959266 2022-09-16

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

AstraZeneca

Phase 1 Terminated
5 enrolled
Other solid neoplasm

Advanced Solid Tumours

NCT05008913 2022-09-06

ADME

AstraZeneca

Phase 1 Terminated
2 enrolled
Other solid neoplasm

Advanced Solid Tumors

NCT04949425 2022-09-02

A Study to Assess the Safety and Tolerability of Adavosertib for Patients With Advanced Solid Tumours

AstraZeneca

Phase 1 Terminated
3 enrolled
Other solid neoplasm

Advanced Solid Tumours

NCT02087241 2017-03-29

Ph II Trial of Carboplatin and Pemetrexed With or Without AZD1775 for Untreated Lung Cancer

AstraZeneca

Phase 2 Terminated
22 enrolled 15 charts
Thoracic

Lung Neoplasms

NCT02087176 2016-06-14

A Placebo Controlled Study Comparing AZD1775+ Docetaxel Versus Placebo+Docetaxel to Treat Lung Cancer

AstraZeneca

Phase 2 Terminated
48 enrolled 11 charts
Thoracic

Previously Treated Non Small Cell Lung Cancer

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