Clinical Trials

132 enrolled

Colorectal Neoplasms

NCT03172299 2025-03-24

PROTECT

Phase 3 Completed

57 enrolled

Dermatologic

Uveal Melanoma

NCT01652196 2025-02-05

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

56 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02384759 2024-07-10

FOLFA

117 enrolled 12 charts

Colorectal Neoplasms

NCT03530267 2024-02-23

ELDERLY

124 enrolled

Colorectal Neoplasms

NCT01782443 2023-08-14

Ziv-Aflibercept for Advanced Progressive Carcinoid Tumors

19 enrolled 11 charts

Endocrine

Carcinoid Tumor, Neoplasm Metastasis

NCT03279289 2023-04-13

AFEMA

170 enrolled

Colorectal Neoplasms

NCT03043729 2023-02-06

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

119 enrolled

Rectal Neoplasms

NCT02181556 2021-06-07

Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer

41 enrolled 8 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT02340949 2021-05-03

RIA

180 enrolled 15 charts

Rectal Neoplasms

NCT04810585 2021-03-23

Plasma Biomarker for Aflibercept in Advanced Colorectal Cancer

Phase 4 Unknown

153 enrolled

Recurrence, Colorectal Neoplasms

NCT01669720 2020-02-17

C261

Phase 2 Terminated

10 enrolled 7 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT01747551 2020-02-10

FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer

64 enrolled 11 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT04252456 2020-02-05

DISTINCTIVE

Phase NA Unknown

150 enrolled

Advanced Colorectal Cancer

NCT02331927 2019-09-20

PERMAD

Phase 2 Unknown

150 enrolled

Colorectal Neoplasms

NCT02624726 2019-02-22

MINOAS

Phase 2 Unknown

31 enrolled

Colorectal Neoplasms

NCT01661972 2018-10-29

X-TRAP

Phase 1/2 Completed

63 enrolled 12 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT01843725 2018-01-31

MOMENTUM1

Phase 1 Completed

37 enrolled

BreastGastrointestinal

Biliary Tract Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02129257 2017-10-24

AMALTHEA

73 enrolled

Colorectal Neoplasms

NCT03264274 2017-08-31

AUSCOR

Neoplasm Metastasis, Colorectal Neoplasms

NCT02079220 2017-07-31

A Phase II Study of Ziv-aflibercept in Combination With Capecitabine/Oxaliplatin (XELOX) Chemotherapy in the Front-Line Treatment of Patients With Metastatic Colorectal Cancer

Colorectal Neoplasms

NCT01802684 2017-03-01

VELVET

49 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT01749956 2017-02-07

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

39 enrolled 13 charts

Rectal Neoplasms

NCT02045030 2016-11-16

Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer

Phase 2 Terminated

14 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT02235324 2015-05-06

Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer

Colonic Neoplasms, Rectal Neoplasms

NCT01941173 2014-07-21

Short-Infusion Ziv-aflibercept in Treating Patients With Metastatic Colorectal Cancer Receiving Combination Chemotherapy

Phase NA Withdrawn

Colonic Neoplasms, Rectal Neoplasms

NCT00601991 2013-04-02

A Multi-Center Phase 2 Study of VEGF Trap as a Single Agent in Acute Myeloid Leukemia