Clinical Trials Browser

Phase 1 × INDUSTRY × capmatinib × Clear all

EGFR-mutant Non-small Cell Lung Cancer

NCT03742349 2025-05-18

Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

Phase 1 Terminated

64 enrolled

Breast

Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT01324479 2020-12-19

Study of INC280 in Patients With c-MET Dependent Advanced Solid Tumors

Phase 1 Completed

131 enrolled

CNSThoracic

Carcinoma, Non-Small-Cell Lung, Glioblastoma

NCT01546428 2020-12-19

A Phase I Study of INC280 in Japanese Patients With Advanced Solid Tumors

Phase 1 Completed

44 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT02925104 2020-12-19

A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors.

Phase 1 Completed

36 enrolled

Other solid neoplasm

cMET Dysegulation Advanced Solid Tumors

NCT02474537 2020-12-10

INC280 in Healthy Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function

Phase 1 Completed

31 enrolled

Hepatic Impairment

NCT02520752 2020-12-10

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

Phase 1 Completed

37 enrolled

Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

NCT02626234 2020-12-10

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

Phase 1 Completed

32 enrolled

Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

NCT02205398 2019-01-22

Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy

Phase 1 Terminated

13 enrolled

GastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01072266 2017-11-22

A Dose-escalation Study in Subjects With Advanced Malignancies

Phase 1 Completed

45 enrolled

Tumor-Agnostic

Neoplasm Metastasis

Clinical Trials

Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC

Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

Study of INC280 in Patients With c-MET Dependent Advanced Solid Tumors

A Phase I Study of INC280 in Japanese Patients With Advanced Solid Tumors

A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors.

INC280 in Healthy Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy

A Dose-escalation Study in Subjects With Advanced Malignancies