Clinical Trials

15 enrolled 18 charts

Breast

Breast Neoplasms

NCT05534646 2026-02-02

Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

Phase 2 Recruiting

100 enrolled

Prostatic Neoplasms

NCT02429843 2021-06-28

A Study of TRC105 in Combination With Paclitaxel/Carboplatin and Bevacizumab in Non-Squamous Cell Lung Cancer

16 enrolled

Thoracic

Lung Neoplasms

NCT03418324 2020-12-30

Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy

11 enrolled 17 charts

Prostatic Neoplasms

NCT01806064 2020-10-19

Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell Carcinoma

Phase 1/2 Terminated

173 enrolled 17 charts

Carcinoma, Renal Cell

NCT02560779 2020-07-17

Trial of TRC105 and Sorafenib in Patients With HCC

27 enrolled 11 charts

Gastrointestinal

Carcinoma, Hepatocellular

NCT03181308 2020-06-24

Study of Carotuximab (TRC105) Plus Nivolumab in Patients With Metastatic NSCLC

11 enrolled 11 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01975519 2020-05-20

A Phase 1B Dose-escalation and Phase 2a Study of Carotuximab (TRC105) in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma

111 enrolled 15 charts

Sarcoma

Hemangiosarcoma, Sarcoma

NCT02979899 2020-05-12

TAPPAS

Phase 3 Completed

128 enrolled 13 charts

Sarcoma

Hemangiosarcoma

NCT03780010 2019-10-28

Study of TRC105 + Paclitaxel/Carboplatin and Bevacizumab in Patients With NSCLC

15 enrolled 14 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02664961 2019-07-23

Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN)

Phase 2 Terminated

3 enrolled 11 charts

Gynecologic

Choriocarcinoma, Trophoblastic Tumor, Placental Site, Gestational Trophoblastic Disease

NCT01564914 2019-06-12

105GM201

22 enrolled 11 charts

CNS

Glioblastoma

NCT02396511 2019-06-11

TRC105 Combined With Standard-dose Bevacizumab for Two Patients With Metastatic And Refractory Choriocarcinoma

2 enrolled 10 charts

Choriocarcinoma

NCT01326481 2019-03-18

TRC105

19 enrolled 9 charts

Breast

Breast Neoplasms

NCT01381861 2019-03-05

Evaluation of TRC105 in the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma

23 enrolled 12 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01306058 2019-01-23

Sorafenib and TRC105 in Hepatocellular Cancer

27 enrolled 32 charts

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms, Liver Neoplasms, Experimental, Adenoma, Liver Cell

NCT01332721 2018-12-05

Study of TRC105 Combined With Standard-Dose Bevacizumab for Advanced Solid Tumors for Which Bevacizumab is Indicated

38 enrolled 8 charts

Other solid neoplasm

Adult Solid Tumor

NCT01727089 2018-08-28

Bevacizumab With or Without TRC105 in Treating Patients With Metastatic Kidney Cancer

59 enrolled 12 charts

Carcinoma, Renal Cell

NCT01648348 2018-05-23

Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme

116 enrolled 17 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01090765 2018-05-22

A Phase I/II Study of TRC105 in Metastatic Castrate Resistant Prostate Cancer (CRPC)

21 enrolled 17 charts

Neoplasms, Prostatic Neoplasms

NCT01375569 2017-07-28

TRC105 for Liver Cancer That Has Not Responded to Sorafenib

11 enrolled 10 charts

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT01328574 2017-01-13

TRC105 in Adults With Advanced/Metastatic Urothelial Carcinoma

13 enrolled 15 charts