Announcements Trials
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Phase

Phase 1 9Phase 2 5Phase 3 3Phase EARLY_PHASE1 1Phase 1/2 1

Status

Terminated 7Completed 5Withdrawn 2Unknown 2Recruiting 2Not yet recruiting 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 5CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 4Adenocarcinoma of Lung 3Lung Neoplasms 2Brain Neoplasms 1

Interventions

Cyclophosphamide 739Cisplatin 687Gemcitabine 641Bevacizumab 615Carboplatin 604Paclitaxel 600Docetaxel 565Radiotherapy 536Fluorouracil 405Oxaliplatin 387Rituximab 369Doxorubicin 360Capecitabine 342Filgrastim 333Etoposide 328Dexamethasone 312Irinotecan 309pembrolizumab 279Leucovorin 274Cetuximab 267Cytarabine 242Erlotinib Hydrochloride 231Prednisone 227Nivolumab 227Trastuzumab 225Bortezomib 221Vincristine 220Methotrexate 207Pemetrexed 199fludarabine phosphate 195

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 2 × Completed × ceritinib × Clear all
NCT02450903 2021-03-30

LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.

Novartis

Phase 2 Completed
20 enrolled 12 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02276027 2020-12-16

A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer

Novartis

Phase 2 Completed
66 enrolled 18 charts
Thoracic

Adenocarcinoma of Lung

NCT02336451 2020-04-21

Ascend-7

Novartis

Phase 2 Completed
156 enrolled 39 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT01685138 2019-03-26

LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer

Novartis

Phase 2 Completed
124 enrolled 18 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01685060 2017-06-19

LDK378 in Adult Patients With ALK-activated NSCLC Previously Treated With Chemotherapy and Crizotinib

Novartis

Phase 2 Completed
140 enrolled 17 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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