Clinical Trials Browser

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Healthy Volunteers

NCT05924152 2024-03-13

A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib

Phase 1 Completed

16 enrolled

Healthy Adults

NCT01428635 2023-09-26

Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy

Phase 2/3 Completed

21 enrolled 10 charts

Classical hematologyMyeloidOther hematologic neoplasm

Blast Crisis, Thrombocytopenia, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Primary Myelofibrosis

NCT01772420 2023-07-27

Phase II Study of Lenalidomide and Eltrombopag in Patients With Symptomatic Anemia

Phase 2 Completed

52 enrolled 21 charts

Classical hematologyOther hematologic neoplasm

Anemia, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelomonocytic, Chronic

NCT01168921 2023-03-23

Phase II Eltrombopag in Chronic Lymphocytic Leukemia (CLL)

Phase 2 Completed

23 enrolled 9 charts

Classical hematologyLymphoidOther hematologic neoplasm

Jacobs syndrome, Leukemia, Thrombocytopenia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT01957176 2022-12-30

A Rollover Study to Provide Continued Treatment With Eltrombopag

Phase 4 Completed

22 enrolled 9 charts

Classical hematologyMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Thrombocytopenia, Leukemia, Myeloid, Acute, Purpura, Thrombocytopenic, Idiopathic

NCT02323178 2021-04-20

A Study of Eltrombopag in Patients With CMML and Thrombocytopenia

Phase 1/2 Completed

30 enrolled

Classical hematologyOther hematologic neoplasm

Thrombocytopenia, Leukemia, Myelomonocytic, Chronic

NCT01893372 2020-02-18

Eltrombopag With or Without Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS)

Phase 2 Completed

29 enrolled 12 charts

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes

NCT01890746 2019-09-11

A Safety and Efficacy Study of Eltrombopag in Subjects With AML

Phase 2 Completed

148 enrolled 42 charts

Classical hematologyOther hematologic neoplasm

Leukemia, Thrombocytopenia, Leukemia, Myeloid, Acute

NCT01286675 2019-03-01

Effect of Eltrombopag Plus G-CSF on Human CD34+ Cell Mobilization in Multiple Myeloma Patients Undergoing ASCT

Phase EARLY_PHASE1 Completed

19 enrolled

Plasma cell

Multiple Myeloma

NCT01610180 2018-07-16

Eltrombopag for the Treatment of Immune ThrombocytoPenia (ITP) Secondary to Chronic Lymphoproliferative Disorders (LPDs)

Phase 2 Completed

18 enrolled

LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Purpura, Thrombocytopenic, Idiopathic

NCT00358540 2017-11-13

Dose Finding Study Of Oral Eltrombopag In Patients With Sarcoma Receiving Adriamycin And Ifosfamide

Phase 1 Completed

18 enrolled

Classical hematologySarcoma

Sarcoma, Thrombocytopenia

NCT01440374 2017-06-05

ASPIRE

Phase 2 Completed

162 enrolled 24 charts

Classical hematologyMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Thrombocytopenia, Leukemia, Myeloid, Acute

NCT00102726 2017-03-23

SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy

Phase 2 Completed

183 enrolled

Classical hematology

Jacobs syndrome, Thrombocytopenia

NCT01488565 2016-02-15

Aza-E

Phase 2 Completed

25 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

Clinical Trials

BCRPmarker

A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib

Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy

Phase II Study of Lenalidomide and Eltrombopag in Patients With Symptomatic Anemia

Phase II Eltrombopag in Chronic Lymphocytic Leukemia (CLL)

A Rollover Study to Provide Continued Treatment With Eltrombopag

A Study of Eltrombopag in Patients With CMML and Thrombocytopenia

Eltrombopag With or Without Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS)

A Safety and Efficacy Study of Eltrombopag in Subjects With AML

Effect of Eltrombopag Plus G-CSF on Human CD34+ Cell Mobilization in Multiple Myeloma Patients Undergoing ASCT

Eltrombopag for the Treatment of Immune ThrombocytoPenia (ITP) Secondary to Chronic Lymphoproliferative Disorders (LPDs)

Dose Finding Study Of Oral Eltrombopag In Patients With Sarcoma Receiving Adriamycin And Ifosfamide

ASPIRE

SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy

Aza-E