Clinical Trials Browser

Breast Diseases, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Digestive System Neoplasms, Endocrine Gland Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02909452 2022-01-25

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Phase 1 Completed

30 enrolled

BreastGastrointestinalGenitourinaryThoracic

Breast Diseases, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Digestive System Neoplasms, Endocrine Gland Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02820961 2021-12-15

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

Phase 1 Completed

61 enrolled

Breast

Breast Diseases, Breast Neoplasms

NCT01594398 2021-11-19

ENCORE110

Phase 1 Completed

14 enrolled

BreastThoracic

Breast Diseases, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03538171 2021-07-09

Ph3 Study of Exemestane With or Without Entinostat in Chinese Patients With Hormone Receptor-Positive, Locally Advanced or Metastatic Breast Cancer

Phase 3 Unknown

375 enrolled

Breast

Advanced Breast Cancer

NCT00866333 2019-10-22

ENGAGE-501

Phase 2 Terminated

49 enrolled 12 charts

Lymphoid

Hodgkin Disease

NCT02833155 2019-05-07

Entinostat in Chinese Postmenopausal Women Patients With Locally Recurrent or Metastatic Breast Cancer

Phase 1 Completed

19 enrolled

Breast

Breast Neoplasms

NCT00185302 2015-12-14

Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma

Phase 2 Completed

28 enrolled

Dermatologic

Melanoma

NCT02115594 2014-10-08

ENCORE305

Phase 2 Withdrawn

Breast

Breast Neoplasms

Clinical Trials

MORPHEUS HR+BC

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In

Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer

A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib

Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC

Study of the Effect of the Addition of SNDX-275 (Entinostat) to Continued Aromatase Inhibitor (AI) Therapy in Postmenopausal Women With ER+ Breast Cancer Whose Disease is Progressing

Study of KHK2375 in Subjects With Advanced or Recurrent Breast Cancer

Phase 2 Study of KHK2375 in Subjects With Advanced or Recurrent Breast Cancer

A Phase I, Multicenter, Open Label Study on the Effects of SNDX-275 on Expression of Biomarkers in Subjects With Newly Diagnosed Breast Cancer

ENCORE301

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

ENCORE110

Ph3 Study of Exemestane With or Without Entinostat in Chinese Patients With Hormone Receptor-Positive, Locally Advanced or Metastatic Breast Cancer

ENGAGE-501

Entinostat in Chinese Postmenopausal Women Patients With Locally Recurrent or Metastatic Breast Cancer

Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma

ENCORE305