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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Completed 35Terminated 16Active not recruiting 7Withdrawn 4Recruiting 4Not yet recruiting 3Unknown 1

Sponsor Class

NIH 2OTHER 1INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Gastrointestinal 3Lymphoid 1Breast 1

Conditions

Pancreatic Neoplasms 2Neoplasms 1Lymphoma, T-Cell 1Lymphoma, B-Cell 1Lymphoma 1Esophageal Neoplasms 1Breast Neoplasms 1

Interventions

Cyclophosphamide 128Cisplatin 119Radiotherapy 111pembrolizumab 110Paclitaxel 96Gemcitabine 96Carboplatin 96Nivolumab 76Magnetic Resonance Spectroscopy 76Bevacizumab 76Fluorouracil 74Dexamethasone 73Radiosurgery 66Docetaxel 59Rituximab 58Leucovorin 57Oxaliplatin 55Capecitabine 55Doxorubicin 52fludarabine 51Biopsy 48durvalumab 44Cytarabine 44Drug Therapy 43Etoposide 42fludarabine phosphate 40Pemetrexed 40Radiation 39atezolizumab 36Lenalidomide 35

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Withdrawn × Interventional × entinostat × Clear all
NCT05898828 2024-08-05

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

National Institutes of Health Clinical Center (CC)

Phase 1/2 Withdrawn
Gastrointestinal

Esophageal Neoplasms, Neoplasms

NCT03760614 2021-01-15

A Study of Entinostat and FOLFOX in Subjects With Pancreatic Adenocarcinoma

Abramson Cancer Center at Penn Medicine

Phase 1 Withdrawn
Gastrointestinal

Pancreatic Neoplasms

NCT03925428 2020-09-28

Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas

National Cancer Institute (NCI)

Phase 1 Withdrawn
GastrointestinalLymphoid

Lymphoma, Pancreatic Neoplasms, Lymphoma, B-Cell, Lymphoma, T-Cell

NCT02115594 2014-10-08

ENCORE305

Syndax Pharmaceuticals

Phase 2 Withdrawn
Breast

Breast Neoplasms

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