Clinical Trials Browser

Phase 2 × Interventional × ganitumab × Clear all

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT01318642 2024-11-08

Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas

Phase 2 Terminated

10 enrolled 10 charts

Gastrointestinal

Adenocarcinoma, Pancreatic Neoplasms

NCT00626106 2024-09-19

QUILT-2.015: A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer

Phase 2 Completed

156 enrolled 16 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT04129151 2024-08-01

Palbociclib + Ganitumab In Ewing Sarcoma

Phase 2 Terminated

10 enrolled 15 charts

Sarcoma

Recurrence, Sarcoma, Sarcoma, Ewing

NCT00891930 2024-07-17

Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab

Phase 2 Completed

74 enrolled 15 charts

Gastrointestinal

Colorectal Neoplasms

NCT01327612 2021-02-21

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

Phase 2 Completed

12 enrolled 21 charts

EndocrineGastrointestinalLymphoidSarcomaThoracic

Carcinoid Tumor, Carcinoma, Non-Small-Cell Lung, Lymphoma, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms

NCT01024387 2018-03-08

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Phase 2 Completed

60 enrolled 7 charts

EndocrineNET

Carcinoid Tumor, Adenoma, Islet Cell, Neuroendocrine Tumors

NCT00563680 2016-10-27

QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors

Phase 2 Completed

38 enrolled

Sarcoma

Askin Tumor, Insulin-Like Growth Factor I, Resistance To, Sarcoma, Sarcoma, Ewing, Neuroectodermal Tumors, Primitive

NCT00813605 2016-10-27

QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma

Phase 2 Completed

155 enrolled

Gastrointestinal

Adenocarcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00718523 2016-01-12

Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer

Phase 2 Terminated

170 enrolled 20 charts

Gynecologic

Ovarian Neoplasms

NCT00719212 2016-01-11

Study of AMG 479 as Second Line Therapy in Patients With Recurrent Platinum-sensitive Ovarian Cancer

Phase 2 Completed

61 enrolled 22 charts

Gynecologic

Ovarian Neoplasms

Clinical Trials

I-SPY

Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas

QUILT-2.015: A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer

Palbociclib + Ganitumab In Ewing Sarcoma

Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors

QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma

Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer

Study of AMG 479 as Second Line Therapy in Patients With Recurrent Platinum-sensitive Ovarian Cancer