Announcements Trials
Browse Landscape

Phase

Phase 2 5Phase 1/2 2Phase NA 1Phase EARLY_PHASE1 1Phase 3 1Phase 1 1

Status

Terminated 3Suspended 1Completed 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Sarcoma 2Lymphoid 2Other 1

Conditions

Osteosarcoma 2Renal Insufficiency 1Neoplasms 1Mucositis 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Drug-Related Side Effects and Adverse Reactions 1

Interventions

Cisplatin 1514Carboplatin 1416Cyclophosphamide 1359Gemcitabine 1235Bevacizumab 1223Paclitaxel 1210Radiotherapy 1173Docetaxel 1079pembrolizumab 1026Oxaliplatin 934Capecitabine 898Fluorouracil 832Rituximab 729Doxorubicin 683Nivolumab 679Dexamethasone 665Etoposide 660Irinotecan 622Leucovorin 574Pemetrexed 508Drug Therapy 491Cetuximab 481Trastuzumab 467Cytarabine 466Magnetic Resonance Spectroscopy 457Filgrastim 446Prednisone 432Lenalidomide 409Specimen Handling 407Temozolomide 400

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 2 × Interventional × glucarpidase × Clear all
NCT05022797 2024-05-13

Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS

Fundacion CRIS de Investigación para Vencer el Cáncer

Phase 2 Terminated
3 enrolled
Lymphoid

Lymphoma, Large B-Cell, Diffuse, Drug-Related Side Effects and Adverse Reactions

NCT04668768 2024-03-22

HM-178: Assessing Methods for Improvement in Methotrexate Toxicity Management and Detection of Central Nervous System Involvement of Aggressive Lymphoma

Fox Chase Cancer Center

Phase 2 Suspended
3 enrolled
Lymphoid

Lymphoma

NCT02022358 2015-06-04

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

University College, London

Phase 2 Terminated
34 enrolled
OtherSarcoma

Osteosarcoma, Mucositis

NCT00634322 2014-09-15

High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma

BTG International Inc.

Phase 2 Terminated
7 enrolled 7 charts
Sarcoma

Osteosarcoma

NCT00219791 2014-09-11

Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance

BTG International Inc.

Phase 2 Completed

Neoplasms, Renal Insufficiency

Data powered by HemOnc (CC BY 4.0) Colophon âš¡