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Phase

Phase 2 3Phase 1/2 1

Status

Terminated 4Completed 4Unknown 1Suspended 1Approved for marketing 1Active not recruiting 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Sarcoma 2Other hematologic neoplasm 1Other 1Lymphoid 1

Conditions

Osteosarcoma 2Mucositis 1Lymphoma, Large B-Cell, Diffuse 1Hematologic Neoplasms 1Drug-Related Side Effects and Adverse Reactions 1

Interventions

Cyclophosphamide 241Radiotherapy 217Gemcitabine 187Cisplatin 185Carboplatin 182Docetaxel 166Bevacizumab 166Paclitaxel 144Capecitabine 142Rituximab 141pembrolizumab 140Nivolumab 126Oxaliplatin 124Dexamethasone 122Fluorouracil 113fludarabine 104Radiosurgery 101Doxorubicin 99fludarabine phosphate 97Irinotecan 96Etoposide 95Lenalidomide 93Cytarabine 92Magnetic Resonance Spectroscopy 90Radiation 89Filgrastim 89Leucovorin 88Bortezomib 86Cetuximab 80Pemetrexed 79

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Terminated × OTHER × glucarpidase × Clear all
NCT05022797 2024-05-13

Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS

Fundacion CRIS de Investigación para Vencer el Cáncer

Phase 2 Terminated
3 enrolled
Lymphoid

Lymphoma, Large B-Cell, Diffuse, Drug-Related Side Effects and Adverse Reactions

NCT02022358 2015-06-04

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

University College, London

Phase 2 Terminated
34 enrolled
OtherSarcoma

Osteosarcoma, Mucositis

NCT00634322 2014-09-15

High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma

BTG International Inc.

Phase 2 Terminated
7 enrolled 7 charts
Sarcoma

Osteosarcoma

NCT00424645 2012-12-06

Voraxaze for Delayed Methotrexate Clearance

M.D. Anderson Cancer Center

Phase 1/2 Terminated
3 enrolled 2 charts
Other hematologic neoplasm

Hematologic Neoplasms

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