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Phase

Phase NA 1Phase 3 1Phase 2 1Phase 1/2 1Phase 1 1

Status

Completed 5Terminated 4Unknown 1Suspended 1Approved for marketing 1Active not recruiting 1

Sponsor Class

OTHER 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 3Other hematologic neoplasm 2Sarcoma 1Other 1

Conditions

Renal Insufficiency 2Neurotoxicity Syndromes 2Lymphoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Osteosarcoma 1Neoplasms 1Mucositis 1Lymphoma, Large B-Cell, Diffuse 1Leukemia 1

Interventions

Cyclophosphamide 1495Cisplatin 1431Paclitaxel 1339Radiotherapy 1308Carboplatin 1264Gemcitabine 1225Docetaxel 1134Bevacizumab 1068Fluorouracil 906Doxorubicin 799Dexamethasone 753Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 693Etoposide 674Irinotecan 639Filgrastim 624Nivolumab 585Cytarabine 585Leucovorin 582Vincristine 512Cetuximab 478Prednisone 477Bortezomib 472Trastuzumab 469Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 443Lenalidomide 434

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × glucarpidase × Clear all
NCT00634504 2022-06-06

LVPK

BTG International Inc.

Phase 1 Completed
20 enrolled 9 charts
LymphoidOther hematologic neoplasmSarcoma

Leukemia, Lymphoma, Osteosarcoma, Renal Insufficiency

NCT01305655 2018-09-28

NOPHOCPG2

Nordic Society for Pediatric Hematology and Oncology

Phase 3 Completed
47 enrolled 5 charts
LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00018967 2015-04-30

Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate

National Cancer Institute (NCI)

Phase NA Completed
10 enrolled

Neurotoxicity Syndromes

NCT00219791 2014-09-11

Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance

BTG International Inc.

Phase 2 Completed

Neoplasms, Renal Insufficiency

NCT00727831 2014-01-27

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

University College, London

Phase 1/2 Completed
4 enrolled
LymphoidOther

Lymphoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Mucositis

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