Announcements Trials
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Phase

Phase 2 2Phase 1 2

Status

Completed 4Withdrawn 2

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Tumor-Agnostic 1Thoracic 1Head & Neck 1Gastrointestinal 1

Conditions

Non-Squamous Non-Small Cell Lung Cancer 1Neoplasms 1Head and Neck Neoplasms 1Colorectal Neoplasms 1

Interventions

Cyclophosphamide 1499Cisplatin 1435Paclitaxel 1340Radiotherapy 1310Carboplatin 1267Gemcitabine 1226Docetaxel 1133Bevacizumab 1070Fluorouracil 906Doxorubicin 805Dexamethasone 755Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 700Etoposide 679Irinotecan 639Filgrastim 624Cytarabine 587Nivolumab 586Leucovorin 583Vincristine 517Cetuximab 479Prednisone 478Bortezomib 474Trastuzumab 468Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 444Lenalidomide 436

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × imgatuzumab × Clear all
NCT01326000 2022-11-17

A Study of RO5083945 in Combination With FOLFIRI Versus FOLFIRI Plus Cetuximab or FOLFIRI Alone as Second Line Treatment in Patients With Metastatic Colorectal Cancer

Hoffmann-La Roche

Phase 2 Completed
169 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT00721266 2016-11-02

A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.

Hoffmann-La Roche

Phase 1 Completed
102 enrolled
Tumor-Agnostic

Neoplasms

NCT01046266 2016-09-14

A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma

Hoffmann-La Roche

Phase 1 Completed
62 enrolled
Head & Neck

Head and Neck Neoplasms

NCT01185847 2016-01-01

A Study of RO5083945 in Combination With Chemotherapy Versus Chemotherapy Alone in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

Hoffmann-La Roche

Phase 2 Completed
90 enrolled
Thoracic

Non-Squamous Non-Small Cell Lung Cancer

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