Announcements Trials
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Phase

Phase 2 3Phase 3 1Phase 1/2 1

Status

Completed 5

Sponsor Class

NIH 8OTHER 6INDUSTRY 5NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Genitourinary 2Gastrointestinal 2Head & Neck 1

Conditions

Thyroid Neoplasms 1Prostatic Neoplasms 1Pancreatic Neoplasms 1Metastatic Castration-Resistant Prostate Cancer Patients 1Liver Neoplasms 1

Interventions

pembrolizumab 1033Carboplatin 971Paclitaxel 942Gemcitabine 799Cisplatin 757Docetaxel 698Bevacizumab 637Nivolumab 520Pemetrexed 507Capecitabine 475Cyclophosphamide 473Fluorouracil 425Dexamethasone 410Rituximab 391Oxaliplatin 352Injections 347Trastuzumab 314atezolizumab 312Cetuximab 291Leucovorin 290Irinotecan 271130-nm albumin-bound paclitaxel 257Prednisone 251Ipilimumab 244Doxorubicin 241Lenalidomide 231Fulvestrant 226fludarabine 219durvalumab 211Erlotinib Hydrochloride 196

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × irofulven × Clear all
NCT03643107 2025-01-23

Irofulven in AR-targeted and Docetaxel-Pretreated mCRPC Patients With Drug Response Predictor (DRP®)

Allarity Therapeutics

Phase 2 Completed
15 enrolled
Genitourinary

Metastatic Castration-Resistant Prostate Cancer Patients

NCT00374660 2021-12-08

Study of Irofulven in Combination With Oxaliplatin in Patients With Advanced Solid Tumors

Eisai Inc.

Phase 1/2 Completed
63 enrolled
Gastrointestinal

Liver Neoplasms

NCT00124527 2021-06-16

Study of Irofulven Plus Capecitabine in Patients With Advanced Thyroid Cancer

Eisai Inc.

Phase 2 Completed
35 enrolled
Head & Neck

Thyroid Neoplasms

NCT00124566 2016-01-18

Study of Irofulven in Patients With Hormone-refractory Prostate Cancer

Eisai Inc.

Phase 2 Completed
135 enrolled
Genitourinary

Prostatic Neoplasms

NCT00033735 2012-12-24

Irofulven Compared With Fluorouracil in Treating Patients With Pancreatic Cancer

Eisai Inc.

Phase 3 Completed
158 enrolled
Gastrointestinal

Pancreatic Neoplasms

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