Announcements Trials
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Phase

Phase 1 4Phase 2 2Phase 3 1

Status

Recruiting 21Active not recruiting 9Completed 8Withdrawn 3Terminated 2Not yet recruiting 2Approved for marketing 1

Sponsor Class

INDUSTRY 6OTHER 2

Study Type

Interventional 7Observational 1

Sponsor

Cancer Type

CNS 3Other hematologic neoplasm 2Gastrointestinal 2Tumor-Agnostic 1Sarcoma 1Myeloid 1

Conditions

Glioma 3Leukemia, Myeloid, Acute 2Cholangiocarcinoma 2Recurrence 1Neoplasms, Unknown Primary 1IDH1 Mutation Myeloid Neoplasms 1Chondrosarcoma 1

Interventions

Cyclophosphamide 1499Cisplatin 1435Paclitaxel 1340Radiotherapy 1310Carboplatin 1267Gemcitabine 1226Docetaxel 1133Bevacizumab 1070Fluorouracil 906Doxorubicin 805Dexamethasone 755Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 700Etoposide 679Irinotecan 639Filgrastim 624Cytarabine 587Nivolumab 586Leucovorin 583Vincristine 517Cetuximab 479Prednisone 478Bortezomib 474Trastuzumab 468Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 444Lenalidomide 436

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

8 trials
RecentStart dateEnrollment
Completed × ivosidenib × Clear all
NCT02073994 2026-02-17

Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation

Servier

Phase 1 Completed
174 enrolled
CNSGastrointestinalSarcoma

Chondrosarcoma, Glioma, Cholangiocarcinoma

NCT03343197 2026-02-17

Study of AG-120 and AG-881 in Subjects With Low Grade Glioma

Servier

Phase 1 Completed
49 enrolled
CNS

Glioma

NCT06181734 2026-02-10

CONFIDHENCE

iOMEDICO AG

Completed
8 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT03498521 2025-11-19

CUPISCO

Hoffmann-La Roche

Phase 2 Completed
529 enrolled 16 charts
Tumor-Agnostic

Neoplasms, Unknown Primary

NCT03564821 2025-11-04

IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation

Massachusetts General Hospital

Phase 1 Completed
18 enrolled
Myeloid

IDH1 Mutation Myeloid Neoplasms

NCT04056910 2025-02-27

Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors

University of Pittsburgh

Phase 2 Completed
15 enrolled 14 charts
CNS

Glioma

NCT02989857 2024-08-20

ClarIDHy

Servier

Phase 3 Completed
187 enrolled 34 charts 1 FDA
Gastrointestinal

Cholangiocarcinoma

NCT04176393 2023-02-13

A China Bridging Study of Ivosidenib in r/r AML Subjects With an IDH1 Mutation

CStone Pharmaceuticals

Phase 1 Completed
30 enrolled
Other hematologic neoplasm

Recurrence, Leukemia, Myeloid, Acute

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