Announcements Trials
Browse Landscape

Phase

Phase 1 2Phase 2 1

Status

Recruiting 8Active not recruiting 6Completed 5Not yet recruiting 1Approved for marketing 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 3Observational 2

Sponsor

Cancer Type

Sarcoma 3Other solid neoplasm 2Thoracic 1Head & Neck 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Solid Tumors Harboring NTRK Fusion 2Sarcoma 2Thyroid Neoplasms 1Salivary Gland Neoplasms 1Neoplasms 1Melanoma 1Locally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene Fusion 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1Biliary Tract Neoplasms 1

Interventions

Cyclophosphamide 1495Cisplatin 1431Paclitaxel 1339Radiotherapy 1308Carboplatin 1264Gemcitabine 1225Docetaxel 1134Bevacizumab 1068Fluorouracil 906Doxorubicin 799Dexamethasone 753Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 693Etoposide 674Irinotecan 639Filgrastim 624Nivolumab 585Cytarabine 585Leucovorin 582Vincristine 512Cetuximab 478Prednisone 477Bortezomib 472Trastuzumab 469Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 443Lenalidomide 434

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × larotrectinib × Clear all
NCT02576431 2026-04-28

NAVIGATE

Bayer

Phase 2 Completed
215 enrolled 2 FDA
BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT02122913 2026-02-05

A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Bayer

Phase 1 Completed
75 enrolled 2 FDA
Other solid neoplasm

Solid Tumors Harboring NTRK Fusion

NCT05236257 2024-12-10

EPI VITRAKVI

Bayer

Completed
93 enrolled 14 charts
Sarcoma

Locally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene Fusion

NCT05192642 2023-11-14

A Study Called VICTORIA to Learn More About How Well Larotrectinib Works in Adults With TRK Fusion-positive Cancer by Comparing Larotrectinib Data From Clinical Studies With Data of Other Treatments From Actual Practice

Bayer

Completed
368 enrolled
Other solid neoplasm

Solid Tumors Harboring NTRK Fusion

NCT03056599 2021-09-24

Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma

Presage Biosciences

Phase 1 Completed
23 enrolled
Sarcoma

Sarcoma

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