Clinical Trials Browser

Phase 1 × Completed × lenvatinib × Clear all

NCT03564691 2025-10-07

MK-4830-001

Phase 1 Completed

Neoplasms

NCT02720068 2025-05-30

MK-4280-001

Phase 1 Completed

481 enrolled 36 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Neoplasms

NCT03524326 2025-05-13

Testing Lenvatinib and Cetuximab in Patients With Advanced Head and Neck Squamous Cell Carcinoma and Cutaneous Squamous Cell Carcinoma

Phase 1 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03324373 2025-04-24

Lenvatinib and Everolimus in Renal Cell Carcinoma (RCC)

Phase 1 Completed

Carcinoma, Renal Cell

NCT05303090 2025-02-27

Oncolytic Virotherapy Plus PD-1 Inhibitor and Lenvatinib for Patients With Advanced Pancreatic Cancer

Phase 1 Completed

Gastrointestinal

Pancreatic Ductal Adenocarcinoma

NCT03418922 2024-06-20

A Study of Lenvatinib Plus Nivolumab in Participants With Hepatocellular Carcinoma

Phase 1 Completed

30 enrolled 28 charts

Gastrointestinal

Carcinoma, Hepatocellular

NCT03006926 2023-12-13

A Trial of Lenvatinib Plus Pembrolizumab in Participants With Hepatocellular Carcinoma

Phase 1 Completed

104 enrolled 41 charts

Gastrointestinal

Carcinoma, Hepatocellular

NCT00121719 2023-06-22

An Open Label Dose Escalation Study Of E7080

Phase 1 Completed

82 enrolled 34 charts

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Neoplasms

NCT01268293 2023-06-22

A Study of E7080 in Subjects With Solid Tumor

Phase 1 Completed

9 enrolled 6 charts

Neoplasms

NCT01525394 2023-06-22

A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval

Phase 1 Completed

Lymphoma

NCT02788708 2022-09-19

Lenvatinib and Weekly Paclitaxel for Patients With Recurrent Endometrial or Ovarian Cancer

Phase 1 Completed

Fallopian Tube Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT02935309 2022-05-31

Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma

Phase 1 Completed

Gastrointestinal

Carcinoma, Rectal Neoplasms

NCT03009292 2021-09-28

Pharmacokinetic Study of E7080/Lenvatinib in Chinese Subjects With Solid Tumor

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT03006887 2021-05-20

Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors

Phase 1 Completed

6 enrolled 27 charts

GenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Endometrial Neoplasms

NCT02686164 2019-08-28

Phase 1 Study to Determine the Effect of Lenvatinib (E7080) on the Pharmacokinetics of Midazolam in Subjects With Advanced Solid Tumors

Phase 1 Completed

51 enrolled 11 charts

Neoplasms

NCT02454478 2019-03-19

Study of Lenvatinib in Combination With Everolimus in Participants With Unresectable Advanced or Metastatic Renal Cell Carcinoma (RCC)

Phase 1 Completed

7 enrolled 17 charts

Carcinoma, Carcinoma, Renal Cell

NCT02578316 2017-06-20

A Study to Determine the Metabolism and Elimination of 14C-E7080 in Patients With Advanced Solid Tumors or Lymphomas, Who Are Unsuitable For, or Have Failed, Existing Therapies.

Phase 1 Completed

6 enrolled 19 charts

Lymphoma

NCT00280397 2016-10-07

An Open Label Phase I Dose Escalation Study of E7080 Administered to Patients With Solid Tumors

Phase 1 Completed

27 enrolled 8 charts

Neoplasms

NCT00121680 2015-12-11

A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Combination With Temozolomide in Patients With Advanced and/or Metastatic Melanoma

Phase 1 Completed

Melanoma, Neoplasms

NCT00832819 2015-04-30

E7080 in Combination With Carboplatin and Paclitaxel in Patients With Non-small Cell Lung Cancer (NSCLC)

Phase 1 Completed

28 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT01240408 2015-03-04

E7080 Food Effect Study in Healthy Subjects

Phase 1 Completed

Neoplasms