Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Completed 3Active not recruiting 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 2Other 1

Conditions

Opioid-Induced Constipation 1Gastrointestinal Neoplasms 1Gastroesophageal Reflux 1Colorectal Neoplasms 1Barrett Esophagus 1

Interventions

Cyclophosphamide 1492Cisplatin 1414Paclitaxel 1317Radiotherapy 1261Carboplatin 1250Gemcitabine 1215Docetaxel 1109Bevacizumab 1030Fluorouracil 894Doxorubicin 792Dexamethasone 748Rituximab 719Capecitabine 716Oxaliplatin 700pembrolizumab 680Etoposide 678Irinotecan 634Filgrastim 621Cytarabine 586Leucovorin 579Nivolumab 558Vincristine 515Prednisone 475Cetuximab 465Bortezomib 459Erlotinib Hydrochloride 456Trastuzumab 447Methotrexate 438Lenalidomide 427Pemetrexed 420

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Interventional × linaclotide × Clear all
NCT05107219 2026-04-07

GCC Agonist Signal in the Small Intestine

University of Wisconsin, Madison

Phase 1 Completed
43 enrolled
Gastrointestinal

Barrett Esophagus, Gastroesophageal Reflux, Gastrointestinal Neoplasms

NCT01950403 2024-12-09

Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers

Mayo Clinic

Phase 1 Completed
24 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT02270983 2019-04-08

Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

Forest Laboratories

Phase 2 Completed
254 enrolled 23 charts
Other

Opioid-Induced Constipation

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