Announcements Trials
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Phase

Phase 2 2Phase 1 2

Status

Completed 3Active not recruiting 1

Sponsor Class

OTHER 3INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Gastrointestinal 3Other 1

Conditions

Colorectal Neoplasms 2Opioid-Induced Constipation 1Gastrointestinal Neoplasms 1Gastroesophageal Reflux 1Barrett Esophagus 1

Interventions

Cyclophosphamide 3162Cisplatin 3160Carboplatin 2938Paclitaxel 2673Radiotherapy 2648Gemcitabine 2547pembrolizumab 2331Docetaxel 2157Bevacizumab 2128Fluorouracil 1822Capecitabine 1784Oxaliplatin 1713Dexamethasone 1590Nivolumab 1517Doxorubicin 1477Rituximab 1454Etoposide 1342Magnetic Resonance Spectroscopy 1266Irinotecan 1235Leucovorin 1216Cytarabine 1123Pemetrexed 1062Drug Therapy 1062fludarabine 1050Vincristine 956Specimen Handling 936Prednisone 926Cetuximab 921Lenalidomide 916Trastuzumab 902

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Interventional × linaclotide × Clear all
NCT05107219 2026-04-07

GCC Agonist Signal in the Small Intestine

University of Wisconsin, Madison

Phase 1 Completed
43 enrolled
Gastrointestinal

Barrett Esophagus, Gastroesophageal Reflux, Gastrointestinal Neoplasms

NCT03796884 2026-04-02

Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer

Thomas Jefferson University

Phase 2 Active not recruiting
230 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT01950403 2024-12-09

Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers

Mayo Clinic

Phase 1 Completed
24 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT02270983 2019-04-08

Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

Forest Laboratories

Phase 2 Completed
254 enrolled 23 charts
Other

Opioid-Induced Constipation

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