Clinical Trials Browser

Phase 1 × Completed × lonafarnib × Clear all

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00038584 2018-10-30

A Phase IB Study Of Oral SCH 66336 Preoperatively In Patients With Head And Neck Squamous Cell Cancer

Phase 1 Completed

37 enrolled

Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00003956 2013-04-04

Combination Chemotherapy in Treating Patients With Advanced Cancer

Phase 1 Completed

25 enrolled

LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00612651 2013-02-20

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

Phase 1 Completed

37 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00068757 2012-09-12

Lonafarnib, Trastuzumab, and Paclitaxel in Treating Patients With HER2/Neu-Overexpressing Stage IIIB, Stage IIIC, or Stage IV Breast Cancer

Phase 1 Completed

23 enrolled

Breast

Breast Neoplasms, Breast Neoplasms, Male

NCT00015899 2009-10-14

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Phase 1 Completed

53 enrolled

CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

Clinical Trials

Study of Lonafarnib and Gleevec in Chronic Myelogenous Leukemia

A Phase IB Study Of Oral SCH 66336 Preoperatively In Patients With Head And Neck Squamous Cell Cancer

Combination Chemotherapy in Treating Patients With Advanced Cancer

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

Lonafarnib, Trastuzumab, and Paclitaxel in Treating Patients With HER2/Neu-Overexpressing Stage IIIB, Stage IIIC, or Stage IV Breast Cancer

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors