Announcements Trials
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Phase

Phase 4 1Phase 3 1Phase 2 1

Status

Completed 8Active not recruiting 6Terminated 5Not yet recruiting 1No longer available 1

Sponsor Class

INDUSTRY 6OTHER 3NETWORK 1

Study Type

Observational 3Interventional 3

Sponsor

Cancer Type

Thoracic 6

Conditions

Carcinoma, Non-Small-Cell Lung 4Non-Small Cell Lung Cancer ALK-positive 1Lung Neoplasms 1Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer 1

Interventions

pembrolizumab 184Carboplatin 132Paclitaxel 101Cisplatin 101Gemcitabine 86Pemetrexed 79durvalumab 75Nivolumab 66Docetaxel 56atezolizumab 52Bevacizumab 50Cyclophosphamide 49Dexamethasone 45Capecitabine 45Oxaliplatin 43130-nm albumin-bound paclitaxel 41Rituximab 40Fulvestrant 39Lenalidomide 38Fluorouracil 38Prednisone 32osimertinib 31olaparib 29Leucovorin 29venetoclax 28fludarabine 28Trastuzumab 27Doxorubicin 27Etoposide 25Cetuximab 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Active not recruiting × INDUSTRY × lorlatinib × Clear all
NCT07556549 2026-05-22

A Study to Learn About Study Medicine Lorlatinib, as a First-line Treatment in Chinese Adults With ALK-positive a/mNSCLC

Pfizer

Active not recruiting
50 enrolled
Thoracic

Non-Small Cell Lung Cancer ALK-positive

NCT05297890 2026-05-19

A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer

CStone Pharmaceuticals

Phase 2 Active not recruiting
70 enrolled
Thoracic

Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer

NCT07567352 2026-05-12

A Study to Learn About Patients With Non-Small Cell Lung Cancer (NSCLC) Who Took Lorlatinib as Their First Treatment

Pfizer

Active not recruiting
200 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06678555 2026-02-05

A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer (NSCLC) Which Has Spread Out.

Pfizer

Active not recruiting
35 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05144997 2025-12-17

Lorlatinib Continuation Study

Pfizer

Phase 4 Active not recruiting
76 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03052608 2025-11-25

A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC

Pfizer

Phase 3 Active not recruiting
296 enrolled 28 charts 1 FDA
Thoracic

Carcinoma, Non-Small-Cell Lung

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