Announcements Trials
Browse Landscape

Phase

Phase 4 2Phase 2 2Phase 1 2Phase 1/2 1

Status

Recruiting 9Completed 7Active not recruiting 7Terminated 6Unknown 5Not yet recruiting 4Withdrawn 1

Sponsor Class

INDUSTRY 4OTHER 3

Study Type

Interventional 7Observational 5

Sponsor

Cancer Type

Thoracic 5Tumor-Agnostic 1CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 3Non Small Cell Lung Cancer Metastatic 1Neuroblastoma 1Carcinoma 1Advanced Non-Small Cell Lung Cancer 1

Interventions

Cyclophosphamide 1488Cisplatin 1410Paclitaxel 1316Radiotherapy 1259Carboplatin 1247Gemcitabine 1214Docetaxel 1110Bevacizumab 1029Fluorouracil 894Doxorubicin 786Dexamethasone 746Rituximab 719Capecitabine 716Oxaliplatin 700pembrolizumab 673Etoposide 673Irinotecan 634Filgrastim 621Cytarabine 584Leucovorin 578Nivolumab 557Vincristine 510Prednisone 474Cetuximab 464Bortezomib 457Erlotinib Hydrochloride 456Trastuzumab 448Methotrexate 437Lenalidomide 426Pemetrexed 419

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Completed × Interventional × lorlatinib × Clear all
NCT03909971 2025-11-05

A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China

Pfizer

Phase 2 Completed
109 enrolled 33 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03107988 2025-09-15

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

New Approaches to Neuroblastoma Therapy Consortium

Phase 1 Completed
65 enrolled 38 charts
CNS

Neuroblastoma

NCT04362072 2025-06-11

Study of Lorlatinib In People With ALK-positive Non-small Cell Lung Cancer

Pfizer

Phase 4 Completed
71 enrolled 26 charts
Tumor-Agnostic

Carcinoma

NCT04111705 2025-04-01

ORAKLE

Intergroupe Francophone de Cancerologie Thoracique

Phase 2 Completed
23 enrolled
Thoracic

Non Small Cell Lung Cancer Metastatic

NCT04541706 2024-12-20

Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India

Pfizer

Phase 4 Completed
100 enrolled 10 charts
Thoracic

Advanced Non-Small Cell Lung Cancer

NCT01970865 2024-08-12

A Study Of PF-06463922 An ALK/ROS1 Inhibitor In Patients With Advanced Non Small Cell Lung Cancer With Specific Molecular Alterations

Pfizer

Phase 1/2 Completed
364 enrolled 89 charts 1 FDA
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04541407 2023-05-16

Temodar Plus Tyrosine Kinase Inhibitors for Progressive CNS Disease

University of Colorado, Denver

Phase 1 Completed
1 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

Data powered by HemOnc (CC BY 4.0) Colophon âš¡