NCT03962543 2026-04-08ReNeuSpringWorks Therapeutics, Inc.Phase 2 Active not recruiting114 enrolled 25 charts 3 FDA
NCT05028166 2026-03-27Individual Patient Compassionate Use of MirdametinibSpringWorks Therapeutics, Inc.Available
NCT03905148 2026-01-07Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid TumorsBeOne MedicinesPhase 1 Completed91 enrolled
NCT05580770 2025-02-17Mirdametinib + BGB-3245 in Advanced Solid TumorsSpringWorks Therapeutics, Inc.Phase 1/2 Terminated23 enrolled
NCT01347866 2018-10-29Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced CancerPfizerPhase 1 Terminated105 enrolled 64 charts
NCT00147550 2013-09-13MEK Inhibitor PD-325901 To Treat Advanced Breast Cancer, Colon Cancer, And Melanoma.PfizerPhase 1/2 Terminated79 enrolled
NCT00174369 2009-03-17MEK Inhibitor PD-325901 To Treat Advanced Non-Small Cell Lung CancerPfizerPhase 2 Terminated34 enrolled