Announcements Trials
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Phase

Phase 2 3Phase 3 2Phase 1 1

Status

Completed 11Terminated 6

Sponsor Class

INDUSTRY 6NETWORK 1

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 4Other solid neoplasm 1Gastrointestinal 1Breast 1

Conditions

Carcinoma, Non-Small-Cell Lung 3Solid Tumors 1Pancreatic Neoplasms 1Neoplasms 1Lung Neoplasms 1Esophageal Neoplasms 1Breast Neoplasms 1

Interventions

pembrolizumab 184Carboplatin 130Paclitaxel 123Gemcitabine 122Docetaxel 96Cyclophosphamide 89Nivolumab 88Cisplatin 87Rituximab 71Dexamethasone 68Pemetrexed 64Bevacizumab 64Capecitabine 60atezolizumab 54fludarabine 49Azacitidine 49Fluorouracil 48130-nm albumin-bound paclitaxel 43venetoclax 41Trastuzumab 41Irinotecan 41Cetuximab 40Leucovorin 36Ipilimumab 36Erlotinib Hydrochloride 34Fulvestrant 32Cytarabine 32avelumab 31Oxaliplatin 31Albumin-Bound Paclitaxel 31

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Terminated × INDUSTRY × motesanib diphosphate × Clear all
NCT00369070 2018-01-04

A Phase 2 Trial of AMG 706 or Bevacizumab in Combination With Chemo for Advanced NSCLC

Amgen

Phase 2 Terminated
186 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02629848 2015-12-14

Study of Motesanib (AMG 706) in Combination With Paclitaxel and Carboplatin for Advanced Non-Squamous Non-Small Cell Lung Cancer

Takeda

Phase 3 Terminated
401 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00356681 2015-10-15

A Study of AMG 706 or Bevacizumab, in Combination With Paclitaxel Chemotherapy, as Treatment for Breast Cancer

Amgen

Phase 2 Terminated
282 enrolled
Breast

Breast Neoplasms

NCT00360867 2015-10-15

An Open Label Treatment Extension Study of AMG 706

Amgen

Phase 2 Terminated
94 enrolled
Other solid neoplasm

Solid Tumors

NCT00460317 2015-09-07

MONET1-MOtesanib NSCLC Efficacy and Tolerability Study

Amgen

Phase 3 Terminated
1,450 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT00101907 2014-03-20

Safety of AMG 706 Plus Panitumumab Plus Gemcitabine-Cisplatin in the Treatment of Patients With Advanced Cancer

Amgen

Phase 1 Terminated
41 enrolled 17 charts
GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms, Pancreatic Neoplasms

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