Clinical Trials

Other solid neoplasmThoracic

37 enrolled

Mesothelioma, Malignant

NCT02730416 2025-07-29

Combination Chemotherapy With Nintedanib / Placebo in Endometrial Cancer

146 enrolled

Endometrial Neoplasms

NCT02299141 2025-06-24

Nintedanib in Molecularly Selected Patients With Advanced Non-Small Cell Lung Cancer

20 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung

NCT02496585 2025-04-16

Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis

34 enrolled 10 charts

Lung Neoplasms, Radiation Pneumonitis

NCT02780700 2025-02-03

Nintedanib Alone or in Combination With Capecitabine in Refractory Metastatic Colorectal Cancer [LUME-Colon 2]

1 enrolled 5 charts

Colorectal Neoplasms

NCT02009579 2024-08-07

ENGOT-cx1/BGOG-cx1: 3 Weekly Carboplatin/Paclitaxel With or Without Nintedanib in Cervix Cancer

120 enrolled

Uterine Cervical Neoplasms

NCT02399215 2023-12-26

Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

32 enrolled 12 charts

EndocrineNET

Carcinoid Tumor, Neuroendocrine Tumors

NCT01583322 2023-09-06

CHIVA

188 enrolled

Ovarian Neoplasms

NCT03062943 2022-09-28

LAM

30 enrolled

Lymphangioleiomyomatosis

NCT03287947 2022-08-09

LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma

5 enrolled 12 charts

Appendiceal Neoplasms

NCT02665143 2022-04-08

A Randomized Trial of a Combination of Nintedanib/Placebo in Combination With Induction Chemotherapy for Patients With Refractory or First Relapse Acute Myeloid Leukemia

Other hematologic neoplasm

25 enrolled 7 charts

Leukemia, Myeloid, Acute

NCT03292250 2022-03-29

Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]

180 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02568449 2021-12-09

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent

Other solid neoplasmThoracic

20 enrolled 11 charts

Mesothelioma, Malignant

NCT02808247 2021-09-20

ANITA

80 enrolled

Sarcoma

NCT02531737 2021-08-10

REFRACT

59 enrolled

Lung Neoplasms

NCT01024920 2021-07-19

Compare Safety and Efficacy of BIBF 1120 Versus Sunitinib.

99 enrolled 45 charts

Carcinoma, Renal Cell

NCT02234596 2021-01-25

Nintedanib in Patients With Advanced Esophagogastric Cancer

34 enrolled 9 charts

Esophagogastric Adenocarcinoma

NCT01788982 2020-07-31

Nintedanib(BIBF1120) in Thyroid Cancer

100 enrolled

Head & Neck

Thyroid Neoplasms, Carcinoma, Medullary

NCT02452463 2020-04-06

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

8 enrolled 25 charts

Carcinoma, Non-Small-Cell Lung, Radiation Pneumonitis

NCT01362361 2019-09-19

AIO-KRK-0111

54 enrolled

Colorectal Neoplasms

NCT02389764 2019-07-17

Nintedanib For HER2-Negative Metastatic Inflammatory Breast Cancer (MIBC)

10 enrolled 9 charts

Breast

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT01610869 2019-05-29

METRO-BIBF

117 enrolled

Carcinoma, Fallopian Tube Neoplasms, Neoplasms, Neoplasms by Site, Ovarian Diseases, Ovarian Neoplasms, Recurrence

NCT01669798 2018-10-16

BIBF 1120 in Bevacizumab Resistant, Persistent, or Recurrent Epithelial Ovarian Cancer

32 enrolled 19 charts

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00801294 2017-12-29

A Phase II Trial of Weekly Alternating Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Advanced Colorectal Cancer

46 enrolled

Colorectal Neoplasms

NCT02182063 2017-12-28

A Study With BIBF 1120 in Patients With Hormone Refractory Prostate Cancer

81 enrolled

Prostatic Neoplasms

NCT01004003 2017-10-26

Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

125 enrolled 19 charts

Carcinoma, Hepatocellular

NCT01225887 2017-10-09

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

37 enrolled 11 charts

GenitourinaryGynecologic

Endometrial Adenocarcinoma

NCT01441297 2017-08-25

BIBF 1120 as Second Line Treatment for Small Cell Lung Cancer

24 enrolled

Small Cell Lung Carcinoma

NCT01948141 2017-06-08

Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens

6 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT02856867 2017-05-09

MEGAN

Phase 2 Withdrawn

Tumor-Agnostic

Neoplasm Metastasis

NCT00710762 2016-08-15

A Randomised Placebo-Controlled Phase II Study of Continuous Maintenance Treatment With BIBF 1120 Following Chemotherapy in Patients With Relapsed Ovarian Cancer

89 enrolled 10 charts

Ovarian Neoplasms

NCT02152059 2016-07-06

A Study to Evaluate the Good and Bad Effects of BIBF1120 in Small Cell Lung Cancer Patients Who Have Previously Benefited From First-line Platinum-based Chemotherapy

Phase 2 Withdrawn

Small Cell Lung Carcinoma

NCT00987935 2016-03-10

A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma Patients

134 enrolled 29 charts

Carcinoma, Hepatocellular

NCT02558387 2015-11-20

Trial of BIBF1120 (Nintedanib) in Patients With Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck

Phase 2 Unknown

20 enrolled

Recurrence

NCT02278978 2015-05-12

BIBF1120 in Patients With Advanced FGFR3 Mutated,Overexpressed,or Wild Type Urothelial Carcinoma

Phase 2 Unknown

129 enrolled

Carcinoma, Transitional Cell

NCT00904839 2015-02-04

BIBF 1120 Versus Bevacizumab in Metastatic Colorectal Cancer

128 enrolled 21 charts

Colorectal Neoplasms

NCT00706628 2015-01-15

A Multi-centre 3-arm Randomised Phase II Trial of BIBF 1120 Versus BIBW 2992 Versus Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Hormone-resistant Prostate Cancer

87 enrolled 20 charts

Prostatic Neoplasms

NCT01380782 2014-08-18

BIBF 1120 for Recurrent High-Grade Gliomas

37 enrolled 11 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Recurrence, Gliosarcoma

NCT01251484 2012-10-04

BIBF 1120 in Recurrent Glioblastoma Multiforme