Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 1/2 1Phase 1 1

Status

Recruiting 3Withdrawn 1No longer available 1Active not recruiting 1

Sponsor Class

INDUSTRY 19OTHER 6NETWORK 2NIH 1

Study Type

Interventional 5Expanded_access 1

Sponsor

Cancer Type

Sarcoma 2Plasma cell 2Tumor-Agnostic 1Breast 1

Conditions

Neoplasms 3Multiple Myeloma 2Desmoid Tumors 2Paraproteinemias 1Neoplasms, Plasma Cell 1Hematologic Diseases 1Corneal Diseases 1Breast Neoplasms 1Blood Protein Disorders 1

Interventions

Cyclophosphamide 2067Radiotherapy 1990Cisplatin 1856Carboplatin 1560Gemcitabine 1454Paclitaxel 1320Bevacizumab 1320pembrolizumab 1238Docetaxel 1227Oxaliplatin 1184Capecitabine 1178Fluorouracil 1083Dexamethasone 979Magnetic Resonance Spectroscopy 971Nivolumab 936Rituximab 929Drug Therapy 915Surveys and Questionnaires 899Doxorubicin 845Etoposide 843Radiosurgery 816Blood Specimen Collection 816Irinotecan 784Cytarabine 743fludarabine 726Leucovorin 684Surgical Procedures, Operative 640Lenalidomide 618Biopsy 594fludarabine phosphate 569

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
OTHER × nirogacestat × Clear all
NCT05879146 2026-05-15

Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study

M.D. Anderson Cancer Center

Phase 2 Recruiting
40 enrolled
Tumor-Agnostic

Neoplasms

NCT05556798 2026-02-24

A Study of Belantamab Mafodotin in Combination With Nirogacestat and Pomalidomide in People With Multiple Myeloma That Has Not Responded to Treatment or Has Come Back After Treatment

Memorial Sloan Kettering Cancer Center

Phase 1 Active not recruiting
9 enrolled
Plasma cell

Multiple Myeloma

NCT05949099 2025-09-08

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Stanford University

Phase 2 Recruiting
28 enrolled
Sarcoma

Desmoid Tumors

NCT05573802 2023-10-24

A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple Myeloma

Hellenic Society of Hematology

Phase 1/2 Recruiting
36 enrolled
Plasma cell

Blood Protein Disorders, Corneal Diseases, Hematologic Diseases, Multiple Myeloma, Neoplasms, Paraproteinemias, Neoplasms, Plasma Cell

NCT02955446 2019-02-01

Compassionate Use Protocol for PF-03084014 in Patients With Advanced Solid Tumor Malignancies

University of Colorado, Denver

No longer available
Sarcoma

Neoplasms, Desmoid Tumors

NCT02338531 2016-04-29

RHEA

Jules Bordet Institute

Phase 2 Withdrawn
Breast

Breast Neoplasms

Data powered by HemOnc (CC BY 4.0) Colophon âš¡