Announcements Trials
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Phase

Phase 2 2Phase 1 2Phase 3 1

Status

Active not recruiting 8Terminated 5Recruiting 5Completed 5Withdrawn 3No longer available 1Available 1

Sponsor Class

INDUSTRY 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Sarcoma 2Plasma cell 1Other hematologic neoplasm 1Gynecologic 1

Conditions

Desmoid Tumors 2Ovarian Neoplasms 1Neoplasms by Histologic Type 1Multiple Myeloma 1Leukemia 1Granulosa cell tumor of the ovary 1

Interventions

Cyclophosphamide 1495Cisplatin 1431Paclitaxel 1339Radiotherapy 1308Carboplatin 1264Gemcitabine 1225Docetaxel 1134Bevacizumab 1068Fluorouracil 906Doxorubicin 799Dexamethasone 753Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 693Etoposide 674Irinotecan 639Filgrastim 624Nivolumab 585Cytarabine 585Leucovorin 582Vincristine 512Cetuximab 478Prednisone 477Bortezomib 472Trastuzumab 469Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 443Lenalidomide 434

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × nirogacestat × Clear all
NCT04093596 2026-05-13

UNIVERSAL

Allogene Therapeutics

Phase 1 Completed
73 enrolled
Plasma cell

Multiple Myeloma

NCT05348356 2025-12-15

Nirogacestat in Ovarian Granulosa Cell Tumors

SpringWorks Therapeutics, Inc.

Phase 2 Completed
53 enrolled
Gynecologic

Granulosa cell tumor of the ovary, Ovarian Neoplasms

NCT03785964 2025-01-31

DeFi

SpringWorks Therapeutics, Inc.

Phase 3 Completed
142 enrolled 21 charts 1 FDA
Sarcoma

Desmoid Tumors

NCT01981551 2024-02-06

Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
17 enrolled 14 charts
Sarcoma

Desmoid Tumors

NCT00878189 2019-11-12

A Trial In Patients With Advanced Cancer And Leukemia

Pfizer

Phase 1 Completed
72 enrolled 49 charts
Other hematologic neoplasm

Leukemia, Neoplasms by Histologic Type

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