Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 1 2Phase 3 1

Status

Active not recruiting 8Terminated 5Recruiting 5Completed 5Withdrawn 3

Sponsor Class

INDUSTRY 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Sarcoma 2Plasma cell 1Other hematologic neoplasm 1Gynecologic 1

Conditions

Desmoid Tumors 2Ovarian Neoplasms 1Neoplasms by Histologic Type 1Multiple Myeloma 1Leukemia 1Granulosa cell tumor of the ovary 1

Interventions

Cyclophosphamide 1488Cisplatin 1410Paclitaxel 1316Radiotherapy 1259Carboplatin 1247Gemcitabine 1214Docetaxel 1110Bevacizumab 1029Fluorouracil 894Doxorubicin 786Dexamethasone 746Rituximab 719Capecitabine 716Oxaliplatin 700pembrolizumab 673Etoposide 673Irinotecan 634Filgrastim 621Cytarabine 584Leucovorin 578Nivolumab 557Vincristine 510Prednisone 474Cetuximab 464Bortezomib 457Erlotinib Hydrochloride 456Trastuzumab 448Methotrexate 437Lenalidomide 426Pemetrexed 419

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Interventional × nirogacestat × Clear all
NCT04093596 2026-05-13

UNIVERSAL

Allogene Therapeutics

Phase 1 Completed
73 enrolled
Plasma cell

Multiple Myeloma

NCT05348356 2025-12-15

Nirogacestat in Ovarian Granulosa Cell Tumors

SpringWorks Therapeutics, Inc.

Phase 2 Completed
53 enrolled
Gynecologic

Granulosa cell tumor of the ovary, Ovarian Neoplasms

NCT03785964 2025-01-31

DeFi

SpringWorks Therapeutics, Inc.

Phase 3 Completed
142 enrolled 21 charts 1 FDA
Sarcoma

Desmoid Tumors

NCT01981551 2024-02-06

Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
17 enrolled 14 charts
Sarcoma

Desmoid Tumors

NCT00878189 2019-11-12

A Trial In Patients With Advanced Cancer And Leukemia

Pfizer

Phase 1 Completed
72 enrolled 49 charts
Other hematologic neoplasm

Leukemia, Neoplasms by Histologic Type

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