Announcements Trials
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Phase

Phase 2 3Phase 1 2

Status

Active not recruiting 8Terminated 5Recruiting 5Completed 5Withdrawn 3

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Plasma cell 2Breast 2Gastrointestinal 1

Conditions

Multiple Myeloma 2Triple Negative Breast Neoplasms 1Pancreatic Neoplasms 1Breast Cancer Metastatic 1

Interventions

Cyclophosphamide 389Carboplatin 343Gemcitabine 331pembrolizumab 328Cisplatin 327Paclitaxel 294Radiotherapy 291Docetaxel 285Bevacizumab 249Rituximab 233Capecitabine 221Nivolumab 218Dexamethasone 205Fluorouracil 189fludarabine 177Oxaliplatin 177Pemetrexed 153Doxorubicin 152Irinotecan 147Etoposide 144Leucovorin 143Cytarabine 133Bortezomib 129fludarabine phosphate 128Cetuximab 126Lenalidomide 125Filgrastim 119Erlotinib Hydrochloride 119Temozolomide 111Radiosurgery 110

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Terminated × Interventional × nirogacestat × Clear all
NCT05090566 2026-04-24

MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma

Pfizer

Phase 2 Terminated
46 enrolled 15 charts
Plasma cell

Multiple Myeloma

NCT04171843 2023-09-21

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

Precision BioSciences, Inc.

Phase 1 Terminated
48 enrolled
Plasma cell

Multiple Myeloma

NCT01876251 2019-03-15

A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast Cancer

Pfizer

Phase 1 Terminated
30 enrolled 29 charts
Breast

Breast Cancer Metastatic

NCT02109445 2019-01-10

Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapies

Pfizer

Phase 2 Terminated
3 enrolled 15 charts
Gastrointestinal

Pancreatic Neoplasms

NCT02299635 2019-01-08

A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch Alterations

Pfizer

Phase 2 Terminated
19 enrolled 9 charts
Breast

Triple Negative Breast Neoplasms

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