Clinical Trials
34 trialsNCT05015608 2026-05-27
SACHI
Hutchmed
Phase 3 Completed
NCT04181060 2026-05-18
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
National Cancer Institute (NCI)
Phase 3 Recruiting
NCT06417814 2026-05-14
TROPION-Lung15
AstraZeneca
Phase 3 Recruiting
NCT06486142 2026-05-14
ERIS
Region Skane
Phase 3 Recruiting
NCT07376382 2026-05-13
SYNSTAR-02
CSPC Megalith Biopharmaceutical Co.,Ltd.
Phase 3 Not yet recruiting
NCT04487080 2026-05-08
MARIPOSA
Janssen Research & Development, LLC
Phase 3 Active not recruiting
NCT06670196 2026-05-08
A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
Phase 3 Recruiting
NCT06350097 2026-05-06
TROPION-Lung14
AstraZeneca
Phase 3 Recruiting
NCT03521154 2026-05-05
LAURA
AstraZeneca
Phase 3 Active not recruiting
NCT05624996 2026-05-04
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
NRG Oncology
Phase 3 Recruiting
NCT05120349 2026-04-23
ADAURA2
AstraZeneca
Phase 3 Active not recruiting
NCT02296125 2026-04-21
FLAURA
AstraZeneca
Phase 3 Completed
NCT04765059 2026-04-21
COMPEL
AstraZeneca
Phase 3 Active not recruiting
NCT06838273 2026-04-20
A Study of BL-B01D1 in Combination With Osimertinib Versus Osimertinib as First-Line Treatment in Patients With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer(PANKU-Lung04)
Sichuan Baili Pharmaceutical Co., Ltd.
Phase 3 Recruiting
NCT05261399 2026-04-06
SAFFRON
AstraZeneca
Phase 3 Active not recruiting
NCT05629234 2026-04-06
ROSY-T
AstraZeneca
Phase 3 Active not recruiting
NCT02511106 2026-03-30
ADAURA
AstraZeneca
Phase 3 Active not recruiting
NCT06970639 2026-02-12
A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Sensitizing Mutation-Positive Non-squamous Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases
Allist Pharmaceuticals, Inc.
Phase 3 Recruiting
NCT02411448 2026-01-16
RELAY
Eli Lilly and Company
Phase 3 Active not recruiting
NCT04695925 2025-10-15
TOP
Sun Yat-sen University
Phase 3 Active not recruiting
NCT04035486 2025-10-10
FLAURA2
AstraZeneca
Phase 3 Active not recruiting
NCT04351555 2025-05-23
NeoADAURA
AstraZeneca
Phase 3 Active not recruiting
NCT06829459 2025-04-08
A Study to Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs
Shanghai JMT-Bio Inc.
Phase 3 Recruiting
NCT02151981 2025-01-07
AURA3
AstraZeneca
Phase 3 Completed
NCT06735391 2024-12-16
A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations
Shanghai JMT-Bio Inc.
Phase 3 Recruiting
NCT02454933 2024-09-19
CAURAL
AstraZeneca
Phase 3 Completed
NCT06093503 2024-06-26
Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein
AbbVie
Phase 3 Withdrawn
NCT05493501 2024-05-02
Aumolertinib With Chemotherapy or Alone Compared With Osimertinib in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer
EQRx International, Inc.
Phase 3 Terminated
NCT06380348 2024-04-23
JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations
Shanghai JMT-Bio Inc.
Phase 3 Not yet recruiting
NCT06323148 2024-03-21
Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022)
Fudan University
Phase 3 Not yet recruiting
NCT04816214 2024-03-05
GEOMETRY-E
Novartis
Phase 3 Terminated
NCT05382728 2024-01-30
Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO)
TYK Medicines, Inc
Phase 3 Recruiting
NCT05104281 2023-03-29
Osimertinib Combined With Bevacizumab in Patients With Brain Metastasis Epidermal Growth Factor Receptor (EGFR) Mutation Positive Metastatic Non-Small Cell Lung Cancer
Qingdao Central Hospital
Phase 3 Unknown
NCT02972333 2016-11-23
Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M
Shandong Cancer Hospital and Institute
Phase 3 Unknown