Clinical Trials

196 enrolled

Breast Neoplasms

NCT05563220 2026-01-06

ELEVATE

435 enrolled

Breast Neoplasms

NCT06753747 2025-12-03

A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma

45 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT03284957 2025-11-24

AMEERA-1

136 enrolled 60 charts

Breast Neoplasms

NCT05867251 2025-11-19

Study of AVZO-021 in Patients With Advanced Solid Tumors

Phase 1/2 Active not recruiting

430 enrolled

BreastGynecologic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Fallopian Tube Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT03304080 2025-07-18

Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast

44 enrolled

Phase 1/2 Active not recruiting

Breast Diseases, Breast Neoplasms

NCT02605486 2025-07-03

Palbociclib in Combination With Bicalutamide for the Treatment of AR(+) Metastatic Breast Cancer (MBC)

46 enrolled

Breast Neoplasms

NCT06947811 2025-06-04

APEAK

71 enrolled

EGFR Tyrosine Kinase Inhibitors Plus Cyclin-dependent Kinase 4/6 Inhibitor

NCT03844997 2025-05-31

Phase I/II Trial of CPX-351 + Palbociclib in Patients With Acute Myeloid Leukemia

Other hematologic neoplasm

35 enrolled 15 charts

Leukemia, Myeloid, Acute

NCT06940349 2025-04-23

COPS-01

100 enrolled

Other solid neoplasm

Solid Tumors Refractory to Standard Therapy

NCT06895733 2025-03-26

Study of Pazopanib Combined With Palbociclib for Refractory Solid Tumors With Co-amplified in the 11q13(FGF3/4/19/CCND1)

65 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT04494958 2025-03-24

PALBOBIN

24 enrolled 10 charts

Triple Negative Breast Neoplasms

NCT03774472 2025-02-17

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

15 enrolled 11 charts

Phase 1/2 Not yet recruiting

Anatomic Stage I Breast Cancer AJCC v8

NCT06757335 2025-01-03

A Phase I/II Trial to Evaluate Oral HP568 Tablets in Patients with ER+/HER2 Advanced Breast Cancer

204 enrolled

Breast Neoplasms

NCT04946864 2024-08-19

A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer

Phase 1/2 Suspended

65 enrolled

Breast Neoplasms

NCT03560531 2024-08-09

A Study of ZN-c5 in Subjects With Breast Cancer

181 enrolled 36 charts

Breast Neoplasms

NCT03024489 2024-03-15

Palbociclib With Cetuximab and IMRT for Locally Advanced Squamous Cell Carcinoma

27 enrolled

Head & Neck

Head and Neck Neoplasms

NCT03709082 2024-03-05

Palbociclib in Estrogen Receptor Positive (ER+) Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

3 enrolled

HER2-positive Breast Cancer

NCT04720768 2024-01-05

CELEBRATE

78 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT02101034 2023-12-21

PD 0332991 and Cetuximab in Patients With Incurable SCCHN

96 enrolled 17 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03386929 2023-12-18

SPRING

15 enrolled 10 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03054363 2023-11-13

Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer

42 enrolled 16 charts

Breast Neoplasms

NCT03158389 2023-09-28

N²M²

228 enrolled

CNS

Glioblastoma

NCT02448771 2022-10-24

A Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer

36 enrolled 28 charts

Breast Neoplasms

NCT03965845 2022-09-19

A Study of Telaglenastat (CB-839) in Combination With Palbociclib in Patients With Solid Tumors

Other solid neoplasmThoracic

53 enrolled

Solid Tumors

NCT02871791 2022-08-29

Palbociclib With Everolimus + Exemestane In BC

41 enrolled 12 charts

Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

NCT04669587 2022-03-22

ENZENO

106 enrolled

Breast Neoplasms

NCT01823835 2021-06-18

A Study of GDC-0810 Single Agent or in Combination With Palbociclib and/or a Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer

152 enrolled 42 charts

Breast Neoplasms

NCT02349633 2021-06-10

Study For Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)

65 enrolled 61 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02310243 2019-04-16

Study of Palbociclib in MLL-rearranged Acute Leukemias

LymphoidOther hematologic neoplasm

50 enrolled

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02202200 2016-04-18

OPTIMUM