NCT06065748 2026-04-06A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)Hoffmann-La RochePhase 3 Recruiting1,050 enrolled
NCT07174336 2026-03-20A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)Eli Lilly and CompanyPhase 3 Recruiting920 enrolled
NCT06377852 2026-03-18The CDK4/6 Inhibitor Dosing Knowledge (CDK) StudyAmerican Society of Clinical OncologyPhase 3 Recruiting500 enrolled
NCT06757634 2026-02-05Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)Celcuity IncPhase 3 Recruiting674 enrolled