Announcements Trials
Browse Landscape

Phase

Phase 1 5Phase 1/2 1

Status

Completed 4Terminated 1Recruiting 1

Sponsor Class

NIH 9INDUSTRY 6OTHER 2

Study Type

Interventional 6

Sponsor

Cancer Type

Other solid neoplasm 2Tumor-Agnostic 1Thoracic 1Other hematologic neoplasm 1Lymphoid 1Genitourinary 1Gastrointestinal 1

Conditions

Solid Tumor, Adult 1Small Cell Lung Carcinoma 1Neoplasms 1Locally Advanced Rectal Cancer 1Leukemia, Lymphocytic, Chronic, B-Cell 1Advanced Solid Tumors 1

Interventions

pembrolizumab 1033Carboplatin 971Paclitaxel 942Gemcitabine 799Cisplatin 757Docetaxel 698Bevacizumab 637Nivolumab 520Pemetrexed 507Capecitabine 475Cyclophosphamide 473Fluorouracil 425Dexamethasone 410Rituximab 391Oxaliplatin 352Injections 347Trastuzumab 314atezolizumab 312Cetuximab 291Leucovorin 290Irinotecan 271130-nm albumin-bound paclitaxel 257Prednisone 251Ipilimumab 244Doxorubicin 241Lenalidomide 231Fulvestrant 226fludarabine 219durvalumab 211Erlotinib Hydrochloride 196

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
INDUSTRY × peposertib × Clear all
NCT03724890 2025-04-10

Study of Avelumab-M3814 Combinations

EMD Serono

Phase 1 Completed
57 enrolled 56 charts
Tumor-Agnostic

Neoplasms

NCT02516813 2024-10-15

Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy

EMD Serono

Phase 1 Completed
52 enrolled 43 charts
Other solid neoplasm

Advanced Solid Tumors

NCT05868174 2024-05-01

Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors

Telix Pharmaceuticals (Innovations) Pty Limited

Phase 1 Recruiting
36 enrolled
GenitourinaryOther solid neoplasm

Solid Tumor, Adult

NCT03770689 2023-03-21

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

EMD Serono

Phase 1/2 Completed
19 enrolled 21 charts
Gastrointestinal

Locally Advanced Rectal Cancer

NCT03116971 2020-09-16

Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)

EMD Serono

Phase 1 Terminated
2 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT02316197 2020-04-28

Clinical Phase I Study Investigating MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Advanced Solid Tumors or Chronic Lymphocytic Leukemia

Merck KGaA, Darmstadt, Germany

Phase 1 Completed
31 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

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