Announcements Trials
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Phase

Phase 1 5Phase 2 3Phase 1/2 3Phase 3 1

Status

Completed 3Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 12OTHER 5NIH 3NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Other hematologic neoplasm 5Lymphoid 2

Conditions

Leukemia, Myeloid, Acute 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Leukemia, Prolymphocytic, B-Cell 1Leukemia, Lymphocytic, Chronic, B-Cell 1Leukemia 1

Interventions

Cyclophosphamide 416Radiotherapy 276fludarabine 238Gemcitabine 211Cisplatin 203Nivolumab 184pembrolizumab 183Paclitaxel 176Carboplatin 168Magnetic Resonance Spectroscopy 166fludarabine phosphate 156Irinotecan 135Bevacizumab 133Cytarabine 128Capecitabine 124Temozolomide 123Specimen Handling 123Radiosurgery 118Docetaxel 116Biopsy 116Ipilimumab 113Dexamethasone 113Radiation 111Oxaliplatin 110Fluorouracil 110Rituximab 108Etoposide 108Filgrastim 99Lenalidomide 98Everolimus 96

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × OTHER × pevonedistat × Clear all
NCT03479268 2026-04-27

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

City of Hope Medical Center

Phase 1 Active not recruiting
18 enrolled
LymphoidOther hematologic neoplasm

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Prolymphocytic, B-Cell

NCT03009240 2026-04-22

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

City of Hope Medical Center

Phase 1 Completed
12 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT04172844 2024-06-04

PAVE

Medical College of Wisconsin

Phase 1 Terminated
16 enrolled
Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

NCT03349281 2022-10-20

Pevonedistat With VXLD Chemotherapy for Adolescent/Young Adults With Relapsed/Refractory ALL or Lymphoblastic NHL

University of Miami

Phase 1 Completed
6 enrolled
LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03459859 2021-12-28

Pevonedistat and Low Dose Cytarabine in Adult Patients With AML and MDS

University of Miami

Phase 1 Completed
12 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

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