Announcements Trials
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Phase

Phase 2 2Phase 1/2 2Phase 1 1

Status

Terminated 5Completed 4Active not recruiting 3

Sponsor Class

OTHER 5NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 2Other hematologic neoplasm 2Tumor-Agnostic 1Other solid neoplasm 1

Conditions

Leukemia, Myeloid, Acute 2Neoplasm Metastasis 1Mesothelioma 1Leukemia 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Cyclophosphamide 241Radiotherapy 217Gemcitabine 187Cisplatin 185Carboplatin 182Docetaxel 166Bevacizumab 166Paclitaxel 144Capecitabine 142Rituximab 141pembrolizumab 140Nivolumab 126Oxaliplatin 124Dexamethasone 122Fluorouracil 113fludarabine 104Radiosurgery 101Doxorubicin 99fludarabine phosphate 97Irinotecan 96Etoposide 95Lenalidomide 93Cytarabine 92Magnetic Resonance Spectroscopy 90Radiation 89Filgrastim 89Leucovorin 88Bortezomib 86Cetuximab 80Pemetrexed 79

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Terminated × OTHER × pevonedistat × Clear all
NCT04172844 2024-06-04

PAVE

Medical College of Wisconsin

Phase 1 Terminated
16 enrolled
Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

NCT03319537 2024-05-23

Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma

Memorial Sloan Kettering Cancer Center

Phase 1/2 Terminated
9 enrolled 9 charts
Other solid neoplasmThoracic

Mesothelioma

NCT03228186 2023-10-23

Trial of Pevonedistat Plus Docetaxel in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer

University of Michigan Rogel Cancer Center

Phase 2 Terminated
40 enrolled 13 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04800627 2022-12-27

Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor

M.D. Anderson Cancer Center

Phase 1/2 Terminated
2 enrolled 4 charts
Tumor-Agnostic

Neoplasm Metastasis

NCT03709576 2020-12-16

Pevonedistat and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission AML

Milton S. Hershey Medical Center

Phase 2 Terminated
3 enrolled 9 charts
Other hematologic neoplasm

Leukemia, Myeloid, Acute

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