Announcements Trials
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Phase

Phase 2 4Phase 1/2 4Phase 1 4Phase 3 2Phase NA 1Phase EARLY_PHASE1 1Phase 4 1

Status

Completed 3Terminated 1

Sponsor Class

INDUSTRY 4OTHER 2

Study Type

Interventional 4

Sponsor

Cancer Type

Sarcoma 2Gastrointestinal 2Thoracic 1Other hematologic neoplasm 1Head & Neck 1Gynecologic 1Dermatologic 1CNS 1

Conditions

Gastrointestinal Stromal Tumors 2Squamous Cell Carcinoma of Head and Neck 1Recurrence 1Ovarian Neoplasms 1Melanoma 1Leukemia, Myeloid, Acute 1Glioblastoma 1Carcinoma, Non-Small-Cell Lung 1

Interventions

pembrolizumab 242Carboplatin 137Nivolumab 132Gemcitabine 127Paclitaxel 116Cisplatin 105Cyclophosphamide 97Bevacizumab 93Dexamethasone 78Injections 75Pemetrexed 71Docetaxel 71Fluorouracil 68Capecitabine 65Rituximab 61Cetuximab 61atezolizumab 59130-nm albumin-bound paclitaxel 59Oxaliplatin 58Leucovorin 57Ipilimumab 54fludarabine 50Lenalidomide 47Azacitidine 40Irinotecan 39venetoclax 38Fulvestrant 38Albumin-Bound Paclitaxel 36Prednisone 35Trastuzumab 34

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1/2 × INDUSTRY × pexidartinib × Clear all
NCT02401815 2025-02-14

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Cogent Biosciences, Inc.

Phase 1/2 Completed
51 enrolled 32 charts
GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01790503 2020-06-30

A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma

Daiichi Sankyo

Phase 1/2 Completed
65 enrolled 26 charts
CNS

Glioblastoma

NCT02452424 2020-03-05

A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors

Daiichi Sankyo

Phase 1/2 Terminated
78 enrolled 19 charts
DermatologicGastrointestinalGynecologicHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Ovarian Neoplasms, Gastrointestinal Stromal Tumors

NCT01349049 2020-03-02

Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Daiichi Sankyo

Phase 1/2 Completed
90 enrolled 23 charts
Other hematologic neoplasm

Recurrence, Leukemia, Myeloid, Acute

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