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Phase

Phase 1 7Phase 1/2 4Phase 2 2Phase NA 1Phase EARLY_PHASE1 1Phase 4 1Phase 3 1

Status

Completed 4Terminated 2

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Gastrointestinal 1CNS 1Breast 1

Conditions

Recurrence 1Neoplasms 1Neoplasm Metastasis 1Leukemia, Myeloid, Acute 1Glioblastoma 1Gastrointestinal Stromal Tumors 1Breast Neoplasms 1

Interventions

Cyclophosphamide 142Gemcitabine 129Paclitaxel 125Radiotherapy 119Carboplatin 112Cisplatin 111pembrolizumab 110Nivolumab 106Docetaxel 90Rituximab 86Lenalidomide 77Dexamethasone 76Cytarabine 69Bevacizumab 64Fluorouracil 63Etoposide 63Oxaliplatin 62Filgrastim 59Peripheral Blood Stem Cell Transplantation 58Everolimus 58Capecitabine 58fludarabine phosphate 57Doxorubicin 56Temozolomide 55Prednisone 54Irinotecan 53Cetuximab 50fludarabine 48Ipilimumab 48Erlotinib Hydrochloride 48

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1/2 × Completed × pexidartinib × Clear all
NCT02401815 2025-02-14

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Cogent Biosciences, Inc.

Phase 1/2 Completed
51 enrolled 32 charts
GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT01596751 2020-07-17

Phase Ib/II Study of PLX 3397 and Eribulin in Patients With Metastatic Breast Cancer

University of California, San Francisco

Phase 1/2 Completed
67 enrolled 19 charts
Breast

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01790503 2020-06-30

A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma

Daiichi Sankyo

Phase 1/2 Completed
65 enrolled 26 charts
CNS

Glioblastoma

NCT01349049 2020-03-02

Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Daiichi Sankyo

Phase 1/2 Completed
90 enrolled 23 charts
Other hematologic neoplasm

Recurrence, Leukemia, Myeloid, Acute

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