Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 1 2Phase NA 1

Status

Completed 6Unknown 3Not yet recruiting 3Recruiting 2Terminated 1

Sponsor Class

NIH 4OTHER 2

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 3Thoracic 1Other neoplasm 1

Conditions

Neurofibroma, Plexiform 3Neurofibromatosis 1 2Radiation Fibrosis Syndrome 1Precancerous Conditions 1Neurofibromatoses 1Nerve Sheath Neoplasms 1Myofibroma 1Lung Neoplasms 1Leiomyoma 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Cyclophosphamide 1488Cisplatin 1410Paclitaxel 1316Radiotherapy 1259Carboplatin 1247Gemcitabine 1214Docetaxel 1110Bevacizumab 1029Fluorouracil 894Doxorubicin 786Dexamethasone 746Rituximab 719Capecitabine 716Oxaliplatin 700pembrolizumab 673Etoposide 673Irinotecan 634Filgrastim 621Cytarabine 584Leucovorin 578Nivolumab 557Vincristine 510Prednisone 474Cetuximab 464Bortezomib 457Erlotinib Hydrochloride 456Trastuzumab 448Methotrexate 437Lenalidomide 426Pemetrexed 419

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Interventional × pirfenidone × Clear all
NCT03177291 2025-12-05

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
48 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
36 enrolled 13 charts
CNS

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00332033 2017-07-02

Development of a Non-Invasive Treatment for Uterine Leiomyoma (Fibroids)

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
32 enrolled

Leiomyoma, Myofibroma

NCT00053937 2015-04-30

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas

National Cancer Institute (NCI)

Phase 1 Completed
CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT00020631 2013-06-19

Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer

National Cancer Institute (NCI)

Phase NA Completed

Radiation Fibrosis Syndrome

NCT00754780 2012-03-19

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Mayo Clinic

Phase 2 Completed
24 enrolled
CNS

Neurofibromatoses, Neurofibroma, Plexiform

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